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47773

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Phylloquinone (K1)

analytical standard

Synonyme(s) :

Vitamine K1, 2-méthyl-3-phytyl-1,4-naphthoquinone, Phylloquinone, Vitamine K1(20)

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About This Item

Formule empirique (notation de Hill):
C31H46O2
Numéro CAS:
84-80-0
Poids moléculaire :
450.70
Numéro Beilstein :
2568816
Numéro CE :
201-564-2
Numéro MDL:
MFCD00214063
Code UNSPSC :
12164500
ID de substance PubChem :
24871410

Qualité

analytical standard

Forme

oil

CofA (certificat d'analyse)

current certificate can be downloaded

Caractéristiques

standard type fat soluble vitamin

Conditionnement

ampule of 100 mg

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Indice de réfraction

n20/D 1.527 (lit.)

Pf

−20 °C (lit.)

Densité

0.984 g/mL at 25 °C (lit.)

Application(s)

food and beverages

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O

InChI

1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1

Clé InChI

MBWXNTAXLNYFJB-NKFFZRIASA-N

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Catégories apparentées

Description générale

Phylloquinone (K1) is a prenylated naphthoquinone. It is a fat soluble vitamin, produced by plants, green algae and some species of cyanobacteria. It functions as a coenzyme and is important for the synthesis of a number of proteins involved in blood clotting and bone metabolism.

Application

Phylloquinone (K1) may be used as an analytical reference standard for the quantification of the analyte in olive oil, chard, human plasma samples, animal and plant food products using reversed-phase high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
LRAD3004
LRAC9898
LRAC4249
LRAC0031
LRAB7993

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Determination of vitamin K1 content in olive oil, chard and human plasma by RP-HPLC method with UV?Vis detection
Otles S and Cagindi O
Food Chemistry, 100(3), 1220-1222 (2007)
Application of a simplified HPLC assay for the determination of phylloquinone (vitamin K1) in animal and plant food items
Jakob E and Elmadfa I
Food Chemistry, 56(1), 87-91 (1996)
Rogier Caluwé et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 29(7), 1385-1390 (2013-11-29)
Haemodialysis patients suffer from accelerated vascular calcification. The vitamin K-dependent matrix Gla protein (MGP) is one of the most powerful inhibitors of vascular calcification. Haemodialysis patients have high levels of the inactive form of MGP (desphosphorylated-uncarboxylated-MGP, dp-uc-MGP) and may benefit
Thilo Krüger et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(11), 2618-2624 (2013-08-31)
Vascular calcification is an independent risk factor for cardiovascular disease. Once thought to be a passive process, vascular calcification is now known to be actively prevented by proteins acting systemically (fetuin-A) or locally (matrix Gla protein). Warfarin is a vitamin
Joline W J Beulens et al.
The British journal of nutrition, 110(8), 1357-1368 (2013-04-18)
Recent reports have attributed the potential health benefits of vitamin K beyond its function to activate hepatic coagulation factors. Moreover, several studies have suggested that menaquinones, also known as vitamin K2, may be more effective in activating extra-hepatic vitamin K-dependent
Afficher tous les articles scientifiques apparentés

Protocoles

HPLC Analysis of Fat-Soluble Vitamins on Ascentis® Express C18, Methanol Mobile Phase

Separation of Retinyl acetate, analytical standard; δ-Tocopherol, analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Retinol palmitate, analytical standard.

HPLC Analysis of Fat Soluble Vitamins on Ascentis® Express RP-Amide, Acetonitrile Mobile Phase

Separation of Retinyl acetate, analytical standard; Vitamin E acetate, analytical standard; Phylloquinone (K1), analytical standard; Ergocalciferol (D2), analytical standard; Cholecalciferol (D3), analytical standard; (±)-α-Tocopherol, analytical standard; δ-Tocopherol, analytical standard; Retinol palmitate, analytical standard

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