SRP5334

PP2C-γ, active, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• Synonyme(s) : MGC1675, MGC2870, PP2C-GAMMA, PP2CG, PPM1G, PPP2CG
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.32

Propriétés

• Produit recombinant: expressed in baculovirus infected Sf9 cells
• Pureté: ≥70% (SDS-PAGE)
• Forme: buffered aqueous glycerol solution
• Activité spécifique: 1920-2880 nmol/min·mg
• Poids mol.: ~105 kDa
• Numéro d'accès NCBI: NM_177983
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Informations sur le gène: human ... PPM1G(5496)

Description

Description générale

PP2Cγ is a member of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PP2C gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. PP2C gamma is highly expressed in testis, skeletal muscle, and heart. PP2C gamma also plays a main role in regulating cell cycle progression.

Forme physique

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Notes préparatoires

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable