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Key Documents

SAB4300168

Sigma-Aldrich

Anti-phospho-SYT1 (pSer309) antibody produced in rabbit

affinity isolated antibody

Synonyme(s) :

Anti-DKFZp781D2042 antibody produced in rabbit, Anti-P65 antibody produced in rabbit, Anti-SVP65 antibody produced in rabbit, Anti-SYT antibody produced in rabbit, Anti-synaptotagmin I antibody produced in rabbit

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About This Item

Numéro MDL:
MFCD01865319
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

~46 kDa

Espèces réactives

human, rat, mouse

Concentration

1 mg/mL

Technique(s)

indirect immunofluorescence: 1:100-1:200

Isotype

IgG

Séquence immunogène

(G-L-SP-D-P)

Numéro d'accès NCBI

NP_001129277.1

Numéro d'accès UniProt

P21579

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

phosphorylation (pSer309)

Informations sur le gène

human ... SYT1(6857)

Immunogène

Peptide sequence around phosphorylation site of serine 309 (G-L-S(p)-D-P), according to the protein SYT1.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Description de la cible

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Papa Diogop Ndiaye et al.
Theranostics, 9(3), 661-675 (2019-02-28)
Hypoxic zones are common features of metastatic tumors. Due to inactivation of the von Hippel-Lindau gene (VHL), renal cell carcinomas (RCC) show constitutive stabilization of the alpha subunit of the hypoxia-inducible factor (HIF). Thus, RCC represents a model of chronic
Laura Mercurio et al.
Cell death & disease, 9(11), 1104-1104 (2018-11-01)
IL-36 cytokines, a subgroup of IL-1 family, comprise IL-36α, IL-36β, and IL-36γ agonists, abundantly expressed in psoriatic skin, and IL-36RA and IL-38 antagonists. In psoriatic skin, IL-36 cytokines interfere with keratinocyte cornification programs and induce the release of antimicrobial peptides
Huimin Huang et al.
Toxicology and applied pharmacology, 328, 34-45 (2017-05-16)
Acute liver injury (ALI) is characteristic of abrupt hepatic dysfunction and inflammatory response. Activaion of Kupffer cells (KCs) plays a central role in the pathogenesis of ALI. Since the High Mobility Group A protein2 (HMGA2) occurs as a driver at
Tao Ye et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 41(4), 1584-1595 (2017-03-24)
Dysregulation of ubiquitin-associated protein 2-like (UBAP2L) has been reported in tumors, but its role in hepatocellular carcinoma (HCC) progression is unclear. The expression levels of UBAP2L in HCC tissues and HCC cell lines were detected by western blot and quantitative
Kaili Lian et al.
Oncotarget, 8(30), 48889-48904 (2017-04-08)
TIPE3 (TNFAIP8L3) is the transfer protein of phosphoinositide second messengers that promote cancer. Its role in breast cancer has not been evaluated. We report here that TIPE3 protein was significantly upregulated in human breast cancer tissues as compared with adjacent
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