SAB2500080

Anti-APOB antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-ApoB-100, Anti-ApoB-48, Anti-Apolipoprotein B (including Ag(x) antigen), Anti-FLDB
• Numéro MDL: MFCD01092562
• Code UNSPSC : 12352203

Propriétés

• Source biologique: goat
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Espèces réactives: human
• Technique(s): immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Numéro d'accès UniProt: P04114
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... APOB(338)

Description

Description générale

Apolipoprotein B (APOB), a large amphipathic glycoprotein, has hydrophobic lipid-binding and hydrophilic regions. It has a low-density lipoprotein (LDL)-receptor-binding domain. The APOB gene with 29 exons produces two forms, such as apoB-48 and apoB-100 in circulating lipoproteins. This gene is located on human chromosome 2p24.1.

Immunogène

Peptide with sequence C-TDLHLRYQKDKK from the internal region of the protein sequence according to NP_000375.2.

Application

Anti-APOB antibody produced in goat has been used in enzyme-linked immunosorbent assay (ELISA).

Actions biochimiques/physiologiques

Apolipoprotein B (APOB) participates in human lipoprotein metabolism. APOB-48 plays an essential role in the synthesis of chylomicron. APOB-100 is required for the structural component of very-low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and low-density lipoprotein (LDL). APOB is essential in the molecular diagnosis of familial hypercholesterolemia (FH). The hydrophobic lipid-binding and hydrophilic regions are capable of interacting with the aqueous plasma environment.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable