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Key Documents

P2891

Sigma-Aldrich

Plasma

from pig

Synonyme(s) :

Plasma citraté

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About This Item

Numéro MDL:
Code UNSPSC :
12352207
Nomenclature NACRES :
NA.71

Source biologique

pig

Niveau de qualité

Forme

powder

Contient

3.8% trisodium citrate as anticoagulant

Température de stockage

2-8°C

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Description générale

Plasma is the liquid part of the blood and lymphatic fluid, which makes up about half of its volume. Plasma is devoid of cells and, unlike serum, has not clotted. It is prepared from whole blood that is collected with anticoagulants (9:1) and centrifuged to remove cells and cellular debris. Some of the more common proteins found in plasma are albumin and prealbumin, α1-acid glycoprotein, transferrin, lipoproteins (HDL, LDL, and VLDL), immunoglobulins, complement proteins, and coagulation proteins (thrombin, plasminogin, and fibrinogen). Citrated plasma contains citrate (3.8% trisodium citrate) as an anticoagulant.

Plasma contains a variety of proteins with diverse functions. The primary functions of the plasma proteins include the maintenance of colloid osmotic pressure, pH, and electrolyte balance; the transport of metal ions, fatty acids, steroids, hormones, and drugs to various organs of the body; use as a source for amino acids for tissue nourishment; hemostasis and the prevention of thrombosis; the regulation of cellular activity and function through hormone signaling; and defense against invasion through the actions of antibodies and complement components.

Application

Plasma was used as a negative control to analyze porcine immunoglobulins in diets and faeces, using a modified radial immunodiffusion method.

Autres remarques

This product is prepared from pooled porcine blood. It contains 3.8% trisodium citrate as an anticoagulant. It is tested for clotting, which indicates that the clotting factors in the product are active. However, it is not analyzed to determine whether other enzymes present are native or denatured. The resulting plasma is 0.45 microm filtered and lyophilized from the indicated volume.

Notes préparatoires

Whole blood collected with anticoagulants (9:1), pooled, and centrifuged. The resulting plasma is 0.45 μm filtered and lyophilized from the indicated volumes.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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