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Key Documents

I5256

Sigma-Aldrich

IgG from goat serum

reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

Synonyme(s) :

Goat IgG

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Conjugué

unconjugated

Niveau de qualité

Qualité

reagent grade

Pureté

≥95% (SDS-PAGE)

Forme

essentially salt-free, lyophilized powder

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

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Description générale

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections
Goat IgG is purified from normal goat serum by fractionation and ion-exchange chromatography.

Application

Purified IgG may be used as a reference antigen, standard, blocking agent or coating protein in a variety of immunoassays including ELISA, dot immunobinding, Western immunoblotting, immunodiffusion and immunoelectrophoresis. Other applications include starting materials for the preparation of immunogens and solid-phase immunoadsorbents. Goat IgG was used as negative control in immunohistochemical analysis of human heart tissue samples and in preparation of egg-white avidin samples for atomic force microscopy. Goat IgG was used as isotype control antibody in immunohistochemical analysis of tissue sections of human tonsils, colon, small intestine, ileus and spleen.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Diana Di Mattia et al.
Veterinary dermatology, 29(3), 212-e76-212-e76 (2018-03-27)
Head and neck ulcers in cats can arise from allergic and nonallergic disorders, including feline leishmaniosis (FeL). It is important to rule out this aetiological agent in regions that are endemic for canine leishmaniosis, because the drugs used to treat
Virginie Gridelet et al.
Reproduction, fertility, and development, 25(3), 511-522 (2013-03-08)
The present study investigated the first interaction that occurs between the blastocyst and endometrium during implantation. Given the ethical objections to studying implantation in humans, a mouse model was used to study the dialogue between luteinising hormone (LH) and luteinising
Hannah Aucott et al.
Journal of innate immunity, 10(3), 215-227 (2018-02-27)
Neuroinflammation triggered by infection or trauma is the cause of central nervous system dysfunction. High-mobility group box 1 protein (HMGB1), released from stressed and dying brain cells, is a potent neuroinflammatory mediator. The proinflammatory functions of HMGB1 are tightly regulated
Sammy M Tabbah et al.
American journal of perinatology, 35(9), 865-872 (2018-03-14)
Hepcidin, a mediator of innate immunity, binds the iron exporter ferroportin, leading to functional hypoferremia through intracellular iron sequestration. We explored hepcidin-ferroportin interactions in neonates clinically diagnosed with early-onset neonatal sepsis (EONS). Hepcidin and interleukin (IL)-6 were quantified by enzyme-linked
Marlene Brandes et al.
Blood, 102(10), 3693-3701 (2003-07-26)
gamma delta T cells are inadequately defined both in terms of their migration potential and contribution to antimicrobial immunity. Here, we have examined the migration profile of human blood gamma delta T cells and related cell lines and correlated these

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