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G0545

Sigma-Aldrich

Anti-GABAA Receptor (γ2 subunit) (extracellular) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Synonyme(s) :

Anti-γ-Aminobutyric Acid Type A Receptor (γ2 subunit)

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About This Item

Numéro MDL:
MFCD06798448
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

lyophilized powder

Espèces réactives

bovine, mouse, rat, human

Technique(s)

western blot: 1:200 using rat brain membrane

Numéro d'accès UniProt

P18507

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... GABRG2(2566)
mouse ... Gabrg2(14406)
rat ... Gabrg2(29709)

Immunogène

synthetic peptide corresponding to amino acids 39-53 of rat GABAA receptor (γ2 subunit). The sequence is identical in human, mouse, and bovine. In chick, it is 13/15 residues identical.

Forme physique

Lyophilized from phosphate buffered saline, pH 7.4, 1% BSA, and 0.05% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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David F Owens et al.
Nature reviews. Neuroscience, 3(9), 715-727 (2002-09-05)
In the mature brain, GABA (gamma-aminobutyric acid) functions primarily as an inhibitory neurotransmitter. But it can also act as a trophic factor during nervous system development to influence events such as proliferation, migration, differentiation, synapse maturation and cell death. GABA
Esa R Korpi et al.
Progress in neurobiology, 67(2), 113-159 (2002-07-20)
Neurotransmitter receptor systems have been the focus of intensive pharmacological research for more than 20 years for basic and applied scientific reasons, but only recently has there been a better understanding of their key features. One of these systems includes
Carolina A Oliva et al.
International journal of molecular sciences, 24(2) (2023-01-22)
In Octodon degus, the aging process is not equivalent between sexes and worsens for females. To determine the beginning of detrimental features in females and the ways in which to improve them, we compared adult females (36 months old) and
Ann J Johnston et al.
Neurobiology of disease, 64, 131-141 (2014-01-11)
Genetic mutations in voltage-gated and ligand-gated ion channel genes have been identified in a small number of Mendelian families with genetic generalised epilepsies (GGEs). They are commonly associated with febrile seizures (FS), childhood absence epilepsy (CAE) and particularly with generalised

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