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F1010

Sigma-Aldrich

Anti-Mouse Polyvalent Immunoglobulins (G,A,M)−FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Conjugué

FITC conjugate

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Technique(s)

direct immunofluorescence: 1:256

Température de stockage

2-8°C

Modification post-traductionnelle de la cible

unmodified

Description générale

Immunoglobulins are proteins produced by B cells in response to antigen and regulate response to bacteria, and viruses. IgG is the main antibody type found in plasma and extracellular fluid and has a pivotal role in complement fixation and placental transport. IgA has a crucial role in mucosal immunity as it restricts pathogens from entering the mucosal membrane. IgM is the largest antibody having a pentameric structure which regulates polyreactivity and removes apoptotic cells. Anti-mouse polyvalent immunoglobulins (G,A,M)−FITC antibody can be used in direct immunofluorescence and immunoelectrophoresis. Goat anti-mouse polyvalent immunoglobulins (G,A,M)-FITC antibody reacts specifically with mouse IgG, IgA, or IgM.

Immunogène

Purified mouse IgG, IgA and IgM

Application

Anti-mouse polyvalent immunoglobulins (G,A,M)−FITC antibody can be used in immunohistochemistry and flow cytometry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

A C Cunningham et al.
Immunology, 86(2), 279-286 (1995-10-01)
The role of major histocompatibility complex (MHC) and adhesion molecule expression by alveolar epithelium on the modulation of immune responses in the lung is not understood. We have developed efficient methods to isolate, purify and culture human alveolar epithelial cells
Daniel Růzek et al.
Virus research, 137(1), 142-146 (2008-07-08)
We undertook a comparative study of the susceptibility of different tick cell lines to infection with the European subtype of tick-borne encephalitis virus (TBEV), prototype strain Neudoerfl. The growth of TBEV was investigated in lines derived from vector Ixodes ricinus
A Gonzalez-Ruiz et al.
Journal of clinical microbiology, 30(11), 2807-2813 (1992-11-01)
Approximately 10% of the world population is infected with Entamoeba histolytica, but only 10% of the carriers develop symptomatic amebiasis. This discrepancy could be explained by the genotypic differences between the morphologically indistinguishable invasive and noninvasive strains of E. histolytica
S P Wang et al.
Journal of clinical microbiology, 29(7), 1295-1298 (1991-07-01)
A new method for determining the serovars of Chlamydia trachomatis isolates by utilizing fluorescent-antibody staining of inclusions in cell culture is described. Monoclonal antibodies which have been successfully used previously for serotyping in the microimmunofluorescence test were employed. The cell
María Mónica Remedi et al.
International journal of experimental pathology, 90(1), 44-51 (2009-02-10)
The tumour microenvironment, which is largely composed of inflammatory cells, is a crucial participant in the neoplastic process through the promotion of cell proliferation, survival and migration. Neutrophil polymorphonuclear cells (PMNs) induce inflammatory reactions that can be either cytotoxic for

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