C213030

DMT-2′O-TBDMS-rC(ac) Phosphoramidite

configured for ABI

• Synonyme(s) : N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-cytidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
• Formule empirique (notation de Hill): C₄₇H₆₄N₅O₉PSi
• Numéro CAS: 121058-88-6
• Poids moléculaire : 902.10
• Numéro MDL: MFCD09842111
• Code UNSPSC : 12352200
• ID de substance PubChem : 329774948
• Nomenclature NACRES : NA.51

Propriétés

• Source biologique: non-animal source (no BSE/TSE risk)
• Gamme de produits: Proligo Reagents
• Pureté: ≥99% (³¹P-NMR); ≥99.0% (reversed phase HPLC)
• Forme: powder
• Technique(s): oligo synthesis: suitable
• Impuretés: ≤0.3% water content (Karl Fischer); ≤0.5% P(III) Impurities 100-169ppm (³¹P-NMR); ≤0.5% single Impurity (reversed phase HPLC); ≤3% residual Solvent content
• Couleur: white to off-white
• λ: conforms (UV/VIS Identity)
• Adéquation: conforms to structure for H-NMR; conforms to structure for LC-MS
• Compatibilité: configured for ABI
• Profil des nucléosides: base: cytidine; base protecting group: acetyl; 2' protecting group: TBDMS; 5' protecting group: DMT; deprotection: fast/standard; base: cytidine; base protecting group: acetyl; 2' protecting group: methyl; 5' protecting group: DMT; deprotection: fast/standard
• Température de stockage: −20°C
• Chaîne SMILES: COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(C)=O)=NC3=O)(c4ccccc4)c5ccc(OC)cc5
• InChI: 1S/C47H64N5O9PSi/c1-32(2)52(33(3)4)62(58-30-16-28-48)60-42-40(59-44(43(42)61-63(11,12)46(6,7)8)51-29-27-41(49-34(5)53)50-45(51)54)31-57-47(35-17-14-13-15-18-35,36-19-23-38(55-9)24-20-36)37-21-25-39(56-10)26-22-37/h13-15,17-27,29,32-33,40,42-44H,16,30-31H2,1-12H3,(H,49,50,53,54)/t40-,42-,43-,44-,62?/m1/s1
• Clé InChI: QKWKXYVKGFKODW-YOEDQOPESA-N

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable