C1145

Cholesterol–PEG 600

• Synonyme(s) : Cholesterol, water soluble from sheep, Cholesteryl-polyethylene glycol 600 sebacate, Polyethylene glycol 600 mono(cholesteryl) ether sebacate, Polyoxyethyl-cholesteryl sebacate
• Numéro CAS: 69068-97-9
• Numéro MDL: MFCD00151772
• Code UNSPSC : 41141804
• eCl@ss : 39023139
• Nomenclature NACRES : NA.77

Propriétés

• Forme: solid
• Ampleur du marquage: ≥20% cholesterol
• Couleur: light yellow
• Solubilité: H₂O: 60 mg/mL
• Conditions d'expédition: dry ice
• Température de stockage: −20°C

Description

Description générale

Cholesterol is one of the important constituent of all membranes. It is made up of a hydrophobic, planar, a polar hydroxyl group, fused-ring nucleus and a short hydrocarbon tail.

Application

Cholesterol-PEG 600 has been used to evaluate its ability to induce apoptosis in vascular smooth muscle cells. It has also been used to restore cholesterol following depletion by methyl β-cyclodextrin.

Actions biochimiques/physiologiques

Cholesterol acts as an antecedent of steroid hormones. It plays a key role in fetal growth and in brain development.

Forme physique

semisolid to solid

Notes préparatoires

Prepared by method of Proksch, G.J., and Bonderman, D.P., Clin. Chem., 24, 1924 (1978).

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)