468R-1

Claudin-4 (EP417) Rabbit Monoclonal Primary Antibody

• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100; 500
• Conjugué: unconjugated
• Forme d'anticorps: culture supernatant
• Type de produit anticorps: primary antibodies
• Clone: EP417, monoclonal
• Description: For In Vitro Diagnostic Use in Select Regions
• Forme: buffered aqueous solution
• Espèces réactives: human
• Conditionnement: vial of 0.1 mL concentrate (468R-14); vial of 0.1 mL concentrate Research Use Only (468R-14-RUO); vial of 0.5 mL concentrate (468R-15); vial of 1.0 mL concentrate (468R-16); vial of 1.0 mL concentrate Research Use Only (468R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (468R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (468R-17); vial of 7.0 mL pre-dilute ready-to-use (468R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (468R-18-RUO)
• Fabricant/nom de marque: Cell Marque^®
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 (concentrated)
• Isotype: IgG
• Contrôle: lung adenocarcinoma
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Visualisation: membranous
• Informations sur le gène: human ... CLDN4(1364)

Description

Description générale

The claudin-family proteins are a group of tight-junction membranous proteins responsible for paracellular molecular flow between adjacent cells of the epithelium.¹ In normal kidney, claudin-4 plays a key role in paracellular ion reabsorption.² Claudin-4 is expressed in most epithelial cells yet is absent in mesothelial cells, making it of great use in characterizing epithelial malignincies.³ Immunohistochemical identification of this antigen may help identify poorly differentiated lung adenocarcinoma from lesions of mesothelial origin.⁴ Likewise, identification of claudin-4 expression by IHC may be useful in characterizing breast and endometrial lesions.^5,6

Qualité

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

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Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2