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Merck
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Key Documents

363A-1

Sigma-Aldrich

PAX-8 Rabbit Polyclonal Antibody

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

Ig fraction of antiserum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Description

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (363A-14)
vial of 0.5 mL concentrate (363A-15)
bottle of 1.0 mL predilute (363A-17)
bottle of 7.0 mL predilute (363A-18)

Fabricant/nom de marque

Cell Marque™

Technique(s)

immunohistochemistry: 1:25-1:100

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Informations sur le gène

human ... PAX8(7849)

Description générale

PAX-8 is a transcription factor expressed during the embryonic development of Müllerian organs,kidneys, and thyroid, with continued expression in some epithelial cell types of these maturetissues. PAX-8 is a useful marker for neoplasms of gynecologic, renal, and thyroidorigin. This antibody targets the N-terminus of the PAX-8 molecule. This section of the protein isshared with other PAX proteins such as PAX-5 and PAX-6; thus, some cross-reactivitywith these proteins may be observed as evidenced by the labeling of selected lymphocytes, andneuroendocrine cells.

Qualité


IVD
IVD
IVD
RUO

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Biljana Pauzar et al.
Collegium antropologicum, 36 Suppl 2, 79-82 (2013-02-13)
US-guided fine needle aspiration cytology is currently the best diagnostic tool for thyroid nodules. However, it is not sensitive and specific enough for differentiating between benign and malignant follicular tumors. A potentially useful marker for this differentiation is the PAX8-PPARgamma
Control of sheath back bleeding: a simplified approach.
G I Gabliani et al.
Catheterization and cardiovascular diagnosis, 13(6), 427-427 (1987-11-01)
Ping Zhang et al.
Pathology international, 56(5), 240-245 (2006-05-04)
Thyroid transcription factor 1 (TTF1), thyroid transcription factor 2 (TTF2) and paired box gene 8 (Pax8) are demonstrated to play a crucial role for the differentiation and organogenesis of thyroid follicular cells. Their roles in thyroid carcinogenesis are not very
Daisuke Nonaka et al.
The American journal of surgical pathology, 32(10), 1566-1571 (2008-08-30)
The ovary is a common site of involvement for metastasis and the breast is one of the most common sources. Metastatic breast carcinoma can mimic a primary ovarian carcinoma. Pax8 is a crucial transcription factor for organogenesis of the thyroid
Daisuke Nonaka et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 21(2), 192-200 (2007-12-18)
Thyroid-specific transcription factors, Pax8, TTF-1, and TTF-2, are crucial for thyroid organogenesis and differentiation. Compared with TTF-1, the other two markers have scarcely been investigated in surgical pathology. The goal of this study is to evaluate the expressions of these
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