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S6814

Sigma-Aldrich

SynaptoGreen™ C4

≥95% purity (HPLC), solid

Synonyme(s) :

FM1-43, N-(3-triethylammoniumpropyl) -4-(4-(dibutylamino)styryl) pyridinium dibromide, Pyridinium, 4-[2-[4-(dibutylamino)phenyl]ethenyl]- 1-[3-(triethylammonio)propyl]- , dibromide

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About This Item

Formule empirique (notation de Hill):
C30H49Br2N3
Numéro CAS:
149838-22-2
Poids moléculaire :
611.54
Numéro MDL:
MFCD00467815
Code UNSPSC :
12171500
ID de substance PubChem :
329824569
Nomenclature NACRES :
NA.47

product name

SynaptoGreen™ C4, ≥95% (HPLC), solid

Niveau de qualité

100

Pureté

≥95% (HPLC)

Forme

solid

Couleur

dark red

Solubilité

DMSO: soluble
H2O: soluble

εmax

≥50000 at 507-513 nm in methanol

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

−20°C

Chaîne SMILES 

[Br-].[Br-].CCCCN(CCCC)c1ccc(\C=C\c2cc[n+](CCC[N+](CC)(CC)CC)cc2)cc1

InChI

1S/C30H49N3.2BrH/c1-6-11-23-32(24-12-7-2)30-18-16-28(17-19-30)14-15-29-20-25-31(26-21-29)22-13-27-33(8-3,9-4)10-5;;/h14-21,25-26H,6-13,22-24,27H2,1-5H3;2*1H/q+2;;/p-2

Clé InChI

VZUVCAGXYLMFEC-UHFFFAOYSA-L

Catégories apparentées

Description générale

SynaptoGreen™ C4 is an oxonol dye that helps in the rapid detection of an antibiotic′s effect on bacterial viability. It is a fluorescent dye that is used in optical imaging studies to determine synaptic activity by staining synaptic vesicles at the nerve terminal or the neuromuscular junction. It is equivalent to FM1-43.

Application

SynaptoGreen™ C4 has been used to label cultured neurons grown on EM grids for fluorescent labeling, live light microscopy and imaging studies.

Actions biochimiques/physiologiques

A fluorescent nerve terminal dye suitable for monitoring synaptic activity at synapses and at neuromuscular junctions.

Autres remarques

Component of NTSI, also sold individually.

Informations légales

SynaptoGreen is a trademark of Biotium, Inc.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
MKCQ0878
MKCK9991
MKCK5858
MKCK3521
MKCJ5448

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Yalda Moayedi et al.
Scientific reports, 8(1), 9975-9975 (2018-07-04)
Oral mechanoreception is implicated in fundamental functions including speech, food intake and swallowing; yet, the neuroanatomical substrates that encode mechanical stimuli are not well understood. Tactile perception is initiated by intricate mechanosensitive machinery involving dedicated cells and neurons. This signal
Yangbin Gao et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(7), 2275-2280 (2015-02-04)
Auxin binding protein 1 (ABP1) has been studied for decades. It has been suggested that ABP1 functions as an auxin receptor and has an essential role in many developmental processes. Here we present our unexpected findings that ABP1 is neither
Tam H Nguyen et al.
PloS one, 7(5), e36913-e36913 (2012-05-26)
Bulk endocytosis contributes to the maintenance of neurotransmission at the amphibian neuromuscular junction by regenerating synaptic vesicles. How nerve terminals internalize adequate portions of the presynaptic membrane when bulk endocytosis is initiated before the end of a sustained stimulation is
Christopher R Heier et al.
EMBO molecular medicine, 5(10), 1569-1585 (2013-09-10)
Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in breaches of the plasma membrane and chronic inflammation in Duchenne muscular dystrophy (DMD). Current management by glucocorticoids has unclear molecular benefits and harsh side effects. It is uncertain
Roman Pleskot et al.
Frontiers in plant science, 3, 54-54 (2012-05-29)
Phosphatidic acid (PA) is an important intermediate in membrane lipid metabolism that acts as a key component of signaling networks, regulating the spatio-temporal dynamics of the endomembrane system and the cytoskeleton. Using tobacco pollen tubes as a model, we addressed
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