72706
L-Leucine
tested according to Ph. Eur.
Synonyme(s) :
Leucinum, (S)-2-Amino-4-methylpentanoic acid
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About This Item
Formule linéaire :
(CH3)2CHCH2CH(NH2)CO2H
Numéro CAS:
Poids moléculaire :
131.17
Numéro Beilstein :
1721722
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352209
ID de substance PubChem :
Agence
USP/NF
tested according to Ph. Eur.
Pureté
98.5-101.0%
Forme
powder
Couleur
white
Pf
>300 °C (lit.)
Chaîne SMILES
CC(C)C[C@H](N)C(O)=O
InChI
1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
Clé InChI
ROHFNLRQFUQHCH-YFKPBYRVSA-N
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William I A Haynes et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4804-4814 (2013-03-15)
The identification of a hyperdirect cortico-subthalamic nucleus connection highlighted the important role of the subthalamic nucleus (STN) in regulating behavior. However, this pathway was shown primarily from motor areas. Hyperdirect pathways associated with cognitive and motivational cortical regions are particularly
Qian Wang et al.
Journal of the National Cancer Institute, 105(19), 1463-1473 (2013-09-21)
L-type amino acid transporters (LATs) uptake neutral amino acids including L-leucine into cells, stimulating mammalian target of rapamycin complex 1 signaling and protein synthesis. LAT1 and LAT3 are overexpressed at different stages of prostate cancer, and they are responsible for
M Sakamoto et al.
The Journal of clinical endocrinology and metabolism, 56(1), 202-204 (1983-01-01)
Recent studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin from bovine adrenal medulla and human pheochromocytoma have revealed that this precursor molecule contains four copies of methionine-enkephalin (Met-Enk) and one copy each of leucine-enkephalin (Leu-Enk)
T Yoshimasa et al.
The Journal of clinical investigation, 69(3), 643-650 (1982-03-01)
To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with
Sebastian Kalamajski et al.
Matrix biology : journal of the International Society for Matrix Biology, 29(4), 248-253 (2010-01-19)
Small leucine-rich proteoglycans/proteins (SLRPs) are associated with collagen fibril formation, and therefore important for the proper formation of extracellular matrices. SLRPs are differentially expressed in tissues and during pathological conditions, contributing to the development of connective tissue properties. The binding
Chromatograms
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