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Merck
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Key Documents

03117057001

Roche

Bovine Serum Albumin Fraction V, heat shock, fatty acid free

from bovine serum

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About This Item

Code UNSPSC :
12352106
Nomenclature NACRES :
NA.21

Source biologique

bovine

Niveau de qualité

Pureté

≥98%

Forme

lyophilized

Conditionnement

pkg of 100 g

Fabricant/nom de marque

Roche

pH

~7.0

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Description générale

BSA is a single polypeptide chain consisting of about 583 amino acid residues and no carbohydrates. At pH 5-7, it contains 17 intra-chain disulfide bridges and one sulfhydryl group.

Application

  • Pharmacological assays; ion-binding, transport, or immunological studies
  • Fatty acid and lipid research
  • Stabilization of proteins and enzymes against proteolysis and denaturation

Actions biochimiques/physiologiques

The fatty acids that are insoluble in circulating plasma are transported primarily by serum. The human serum albumin and bovine serum albumin share 76% sequence homology. Being the most abundant protein in the circulatory system, it participates in the maintenance of blood pH and carries several endogenous and exogenous compounds, including fatty acids, metal, amino acids, steroids and drugs.

Qualité

Purity: ≥98% albumin (electrophoresis), ≥98% protein
Contaminants: ≤1.2mg total fatty acids/g dry powder, ≤30ppm heavy metals, immunoglobulins are not detectable (by Ouchterlony)

Caractéristiques

Moisture: ≤5%

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Prakrith Vijey et al.
Platelets, 29(6), 583-588 (2018-07-27)
Megakaryocytes (MKs) are specialized precursor cells committed to producing and proliferating platelets. In a cytoskeletal-driven process, mature MKs generate platelets by releasing thin cytoplasmic extensions, named proplatelets, into the sinusoids. Due to knowledge gaps in this process and mounting clinical
Putnam F, et al.
The Plasma Proteins: Structure, Function, and Genetic Control, 5 (2012)
Emilio P Mottillo et al.
Methods in enzymology, 538, 263-278 (2014-02-18)
Intracellular lipolysis is an important cellular process in key metabolic tissues, and while much is known about the enzymatic basis of lipolysis, our understanding of how these processes are organized and regulated within cells is incomplete. Lipolysis takes place on
Rachel D Penrod et al.
Journal of neuroscience methods, 200(1), 1-13 (2011-06-16)
Dendritic spines of striatal Medium Spiny Neurons (MSNs) receive converging dopaminergic and glutamatergic inputs. These spines undergo experience-dependent structural plasticity following repeated drug administration and during disease states like Huntington's and Parkinson's. Thus, understanding the molecular mechanisms leading to structural
Bill X Huang et al.
Journal of the American Society for Mass Spectrometry, 15(8), 1237-1247 (2004-07-28)
Serum albumin is the principal transporter of fatty acids that are otherwise insoluble in circulating plasma. While the crystal structure of human serum albumin (HSA) as well as its binding with fatty acids has been characterized, the three dimensional structure

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