SCC283

SF126 Human Glioblastoma Cell Line

SF126 human glioblastoma cell line is a suitable model for cellular physiology and chemosensitivity studies.

• Code UNSPSC : 41106514

Propriétés

• Application(s): cell analysis

Description

Description générale

Glioblastoma multiforme is the most common and malignant primary brain tumor, with a high recurrence rate and a five-year survival rate of less than 5% (1). Nearly 50% of glioblastomas originate in the frontal or temporal lobes of the brain (1). Glioblastomas are the most aggressive form of cancer, highlighting the importance of relevant human patient-derived cell models for advancing research into characteristics and treatment of this disease.

SF126 is a patient-derived glioblastoma cell line originating from a frontal lobe tumor (2). SF126 cells do not express the glial markers GFAP or glutamine synthetase but are positive for laminin and fibronectin expression in early passages, suggestive of proliferative or transformed mesenchymal cells of glioblastoma (2). SF126 cells exhibit hypertriploidy and fibroblastic morphology in culture and are non-tumorigenic in athymic mice (2).

<bold>Source:</bold>
The SF126 glioblastoma cell line was derived from the left frontal lobe tumor of a 50-year-old female patient (2).

Research Category:
Cancer

Origine de la lignée cellulaire

Human, Cancer Cells

Application

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Conditionnement

&ge;1X10⁶ cells/vial

Qualité

• Each vial contains ≥1X10⁶ viable cells.
• Cells are tested negative for infectious diseases by a Human Essential CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are verified to be of human origin and negative for inter-species contamination from rat, mouse, chinese hamster, Golden Syrian hamster, and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are negative for mycoplasma contamination.
• Each lot of cells is genotyped by STR analysis to verify the unique identity of the cell line.

Stockage et stabilité

Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.

Autres remarques

This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact licensing@emdmillipore.com.

Clause de non-responsabilité

Ce produit, destiné à la recherche scientifique, est soumis à une réglementation spécifique en France, y compris pour les activités d'importation et d'exportation (Article L 1211-1 alinéa 2 du Code de la Santé Publique). L'acheteur (c'est-à-dire l'utilisateur final) est tenu d'obtenir une autorisation d'importation auprès du Ministère français de la Recherche, mentionné à l'article L1245-5-1 II du Code de la Santé Publique. En commandant ce produit, vous confirmez détenir l'autorisation d'importation requise.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable