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Key Documents

MAB8783

Sigma-Aldrich

Anti-SARS Antibody, S Specific, clone 154C

clone 154C, Chemicon®, from mouse

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

154C, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunofluorescence: suitable
neutralization: suitable
western blot: suitable

Conditions d'expédition

wet ice

Description générale

Severe acute respiratory syndrome (SARS) is a viral respiratory illness caused by a coronavirus, called SARS-associated coronavirus (SARS-CoV). Human coronaviruses (HCoVs) were previously only associated with mild diseases. The SARS-CoV genome contains five major open reading frames (ORFs) that encode the replicase polyprotein; the spike (S), envelope (E), and membrane (M) glycoproteins; and the nucleocapsid protein (N). It is an enveloped, positive-sense, single-stranded RNA virus.

Spécificité

SARS-associated coronavirus (SARS-CoV) S proteins.

Immunogène

Epitope: S Specific

Application

Anti-SARS Antibody, S Specific, clone 154C is suitable for the detection of SARS in:
  • Immunofluorescence
  • ELISA
  • Western Blot
  • Immunoblot
  • Neutralization

Optimal dilutions must be determined by the end user.

Research Category
Infectious Diseases

Research Sub Category
Infectious Diseases - Viral

Actions biochimiques/physiologiques

Severe acute respiratory syndrome (SARS) -associated coronavirus′ (SARS-CoV) spike glycoprotein mediates the viral entry by binding to the host cell receptor. SARS spike protein is the target for vaccine development and antibody therapies.

Forme physique

Format: Purified
Purified immunoglobulin. Liquid in 0.02M PB, 0.25M sodium chloride with 0.1% sodium azide as a preservative

Stockage et stabilité

Store at 2 to 8°C for up to 12 months from date of receipt.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses.
Letko M, et al.
Nature microbiology, 5(4), 562-569 (2020)
An imperative need for research on the role of environmental factors in transmission of novel coronavirus (COVID-19).
Qu G, et al.
Environmental Science & Technology, 57(7), 3730-3732 (2020)
An Imperative Need for Research on the Role of Environmental Factors in Transmission of Novel Coronavirus (COVID-19).
Guangbo Qu et al.
Environmental science & technology, 54(7), 3730-3732 (2020-03-24)
The Nucleocapsid Protein of SARS-CoV-2: a Target for Vaccine Development.
Noton K Dutta et al.
Journal of virology, 94(13) (2020-06-18)

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