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MAB2120Z

Sigma-Aldrich

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free

clone ERIC-1, Chemicon®, from mouse

Synonyme(s) :

NeuralCellAdhesionMolecule, CD56, MAB2120

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

ERIC-1, monoclonal

Espèces réactives

human, pig

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

Isotype

IgG1

Adéquation

not suitable for flow cytometry

Numéro d'accès NCBI

NM_000615.5
NM_001076682.2
NM_181351.3

Numéro d'accès UniProt

P13591

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... NCAM1(4684)

Description générale

The previously assigned protein identifier P13592 has been merged into P13591. Full details can be found on the UniProt database.

Spécificité

Recognizes N-CAM expressed on developing and adult neuroectrodermal tissues in Humans. Neuroectodermal tumors also stain including Elioma, ependymoma, neuroblastoma, medulloblastoma, retinoblastoma and teratoma. Oat cell carcinoma and Wilms tumor are also highly reactive. Will react on Natural Killer cells. Recognizes 120, 140 and 180 kDa NCAM isoforms.

Immunogène

Epitope: extracellular
Human Retinoblastoma tumor

Application

Anti-NCAM Antibody, extracellular, clone ERIC-1, Azide free is an antibody against NCAM for use in ELISA, WB, IH.
Immunohistology on frozen tissue sections acetone fixation only.

Immunoblotting: Recognizes 120, 140, and 180 kDa NCAM isoforms.

ELISA: 80 ng/mL

Does not work in flow cytometry.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Growth Cones & Axon Guidance

Neurofilament & Neuron Metabolism

Liaison

Replaces: MAB2122

Forme physique

Format: Purified
Liquid in PBS. Does not contain any preservatives

Stockage et stabilité

Store at -20°C only. Avoid repeated freeze-thaw cycles.

Remarque sur l'analyse

Control
Recommended positive control tissue: Neuroblastoma

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells.
Hauck, SM; Kinkl, N; Deeg, CA; Swiatek-de Lange, M; Schoffmann, S; Ueffing, M
Molecular and cellular biology null
Priyadarsini Kumar et al.
PloS one, 10(8), e0135089-e0135089 (2015-08-13)
Trophoblast differentiation during early placental development is critical for successful pregnancy and aberrant differentiation causes preeclampsia and early pregnancy loss. During the first trimester, cytotrophoblasts are exposed to low oxygen tension (equivalent to~2%-3% O2) and differentiation proceeds along an extravillous

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