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Key Documents

MAB1276

Sigma-Aldrich

Anti-Nuclei & Chromosomes Antibody, histone H1 protein, clone 1415-1

clone 1415-1, Chemicon®, from mouse

Synonyme(s) :

Anti-H1.4, Anti-H1E, Anti-H1F4, Anti-H1s-4, Anti-HIST1H1E, Anti-RMNS, Anti-dJ221C16.5

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

1415-1, monoclonal

Espèces réactives

human, rat

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

Isotype

IgG2a

Numéro d'accès NCBI

NM_005321.2

Numéro d'accès UniProt

P10412

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... H1-1(3024)

Spécificité

Histone specific; stains nuclei and chromosomes of cells of all species including animals and plants. Reacts with preferentially with Histone H1 by ELISA and immunoblotting. MAB1276 produces a speckled nuclear staining pattern in all tissues studies.

Stains nuclei of all human cell types and also stains chromosomes diffusely in metaphase cells. Nuclear staining in interphase cells is intense and diffuse. Antibody reacts with rat cells {Bendeck, 2001}.

Immunogène

Epitope: histone H1 protein

Application

Anti-Nuclei & Chromosomes, histone H1 protein, clone 1415-1 is a high quality Mouse Monoclonal Antibody for the detection of Nuclei & Chromosomes & has been validated in ELISA, WB, ICC, IHC(P).

Forme physique

100 μL Hybridoma Supernatant, concentrated by ammonium sulfate. Buffer: PBS with 0.1% sodium azide.
Format: Purified

Remarque sur l'analyse

Control
POSITIVE CONTROL:

Human tonsil

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Activation of the metaphase checkpoint and an apoptosis programme in the early zebrafish embryo, by treatment with the spindle-destabilising agent nocodazole.
R Ikegami, J Zhang, A K Rivera-Bennetts, T D Yager
Zygote null
Susanne Kaitna et al.
Current biology : CB, 12(10), 798-812 (2002-05-17)
Mitotic chromosome segregation depends on bi-orientation and capture of sister kinetochores by microtubules emanating from opposite spindle poles and the near synchronous loss of sister chromatid cohesion. During meiosis I, in contrast, sister kinetochores orient to the same pole, and
June Guo et al.
Journal of vascular research, 50(4), 279-288 (2013-08-31)
In vitro, insulin has both growth-promoting and vasculoprotective effects. In vivo, the effect of insulin is mainly protective. Insulin treatment (3 U/day) decreases smooth muscle cell (SMC) migration and neointimal growth after carotid angioplasty in normal rats maintained at normoglycemia
Sokjoong Chung et al.
International journal of molecular medicine, 37(5), 1170-1180 (2016-03-18)
The use of mesenchymal stem cells (MSCs) in cell therapy in regenerative medicine has great potential, particularly in the treatment of nerve injury. Umbilical cord blood (UCB) reportedly contains stem cells, which have been widely used as a hematopoietic source
T D Yager et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 75(5), 535-550 (1997-01-01)
We describe a rapid and sensitive method for high-resolution imaging at the cellular and subcellular levels in the whole-mount zebrafish embryo. The procedure involves fixing and staining the embryo, followed by deyolking and flattening it under a cover slip, to
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