GF430-M
HumanKine® IL-6, Human Recombinant Xeno-Free
Synonyme(s) :
IL6, Interleukin-6
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About This Item
Code UNSPSC :
12352202
eCl@ss :
32160405
Nomenclature NACRES :
NA.27
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Description générale
HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
Interleukin-6 (IL-6) is a pro-inflammatory cytokine that seems to be involved in the late stages of CTL generation. Other biological functions also include amplification and the inflammatory response. Combination therapies including IL-6 have been shown to have positive effects on specific malignant tumor types. The accumulation of IL-6 in the CNS is usually detrimental and can contribute to pathology of CNS diseases. IL-6 signaling is negatively regulated by TGF-beta, which down regulates STAT1, STAT3 and ICAM-1 expression. IL-6 expression has been linked to inflammatory bowel disease (IBD) and is also the primary clinical target for IBD.
Application
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Qualité
Bioactivity assay: Determined by the dosedependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic
indicator cell line). ED50 is typically 0.2-1 ng/ml.
indicator cell line). ED50 is typically 0.2-1 ng/ml.
Forme physique
Product is presented in PBS and filtered through a 0.2 micron filter before lyophilization.
Notes préparatoires
HumanKine IL-6 is manufactured using all non-animal reagents and is considered Xeno-Free
Stockage et stabilité
Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
Informations légales
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial
Code de la classe de stockage
13 - Non Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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