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Merck
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Key Documents

GF317

Sigma-Aldrich

TGF-β-III Protein, Human Recombinant Animal Free

TGF-β-III is one of three closely related mammalian members of the large TGF-β superfamily.Recombinant animal free human TGF-β-III is manufactured using all non-animal reagents.

Synonyme(s) :

Transforming Growth Factor Beta 3, TGF-Beta-3, TGF-Beta-III

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About This Item

Code UNSPSC :
12352202
eCl@ss :
32160405
Nomenclature NACRES :
NA.75

Produit recombinant

expressed in E. coli

Niveau de qualité

100

Pureté

>98% (SDS-PAGE and HPLC)

Impuretés

<0.1 μg/mg protein endotoxin (<1 EU/μg)

Numéro d'accès UniProt

P10600

Conditions d'expédition

dry ice

Informations sur le gène

human ... TGFB3(7043)

Catégories apparentées

Description générale

Product Source: E. coli.
TGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily. TGF-β-I, TGF-β-II and TGF-β-III are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β3 regulates molecules involved in cellular adhesion and extracellular matrix formation during the process of palate development. TGF-β3 also plays an essential role in controlling the development of lungs in mammals and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Recombinant TGF-β-III is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

Application

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

Qualité

Determined by TGF-β-III’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.

Forme physique

Product is filtered through a 0.2 micron filter before lyophilization.
Recombinant animal free human TGF-β-III is manufactured using all non-animal reagents

Stockage et stabilité

Store at -20°C for up to 6 months from date of receipt.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

10-13 - German Storage Class 10 to 13

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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