GF312

SCF Protein, Human Recombinant Animal Free

The Stem cell factor also known as ckit ligand, mast cell growth factor & steel factor (SLF), is a widely expressed 28-40kDa type I transmembrane glycoprotein. Recombinant animal free human SCF is manufactured using all non-animal reagents.

• Synonyme(s) : Stem Cell Factor, ckit Ligand, Mast Cell Growth Factor, Stell Factor, MGF
• Code UNSPSC : 12352202
• eCl@ss : 32160405
• Nomenclature NACRES : NA.77

Propriétés

• Produit recombinant: expressed in E. coli
• Niveau de qualité: 100
• Pureté: >98% (SDS-PAGE and HPLC)
• Impuretés: <0.1 μg/mg protein endotoxin (<1EU/μg)
• Numéro d'accès NCBI: NM_000899.3; NM_003994.4
• Numéro d'accès UniProt: P21583
• Conditions d'expédition: dry ice

Description

Description générale

Product Source: E. coli

Stem cell factor (SCF), also known as ckit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

Spécificité

Cross Reactivty
Monkey

Application

Research Category
Stem Cell Research

Research Sub Category
Growth Factors & Receptors

Qualité

Bioactivity assay: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.

Forme physique

Product is filtered through a 0.2 micron filter before lyophilization.

Recombinant animal free human SCF is manufactured using all non-animal reagents

Stockage et stabilité

Store at -20°C for up to 6 months from date of receipt.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1