ABS568

Anti-RBP4 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176)
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Technique(s): western blot: suitable
• Numéro d'accès NCBI: NP_006735
• Numéro d'accès UniProt: P02753
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... RBP4(5950)

Description

Description générale

The role of the protein retinol binding protein 4 (RBP4) has always been understood to be involvement in the transport of vitamin A. However, research has demonstrated that blood levels of RBP4 is closely linked with the development of insulin resistance, which predisposes individuals to type 2 diabetes and is a major risk factor for cardiovascular disease. In addition higher levels of RBP4 were closely associated with other components of metabolic syndrome, including increased body mass index, waist-to-hip ratio, serum triglyceride levels and systolic blood pressure, as well as decreased HDL levels. Further investigations indicate that RBP4 may be a useful biomarker in identifying a predisposition to type 2 diabetes and measuring therapeutic improvement.

Immunogène

Recombinant protein corresponding to human RBP4.

Application

Anti-RBP4 Antibody is a highly specific rabbit polyclonal antibody, that targets Retinol binding protein 4 & has been tested in western blotting.

Research Category
Signaling

Research Sub Category
Metabolic Hormones & Receptors

Western Blotting Analysis: 2.0 µg/mL from a representative lot detected RBP4 in 10 µg of human spleen, thymus, ovary and testis tissue lysates.

Qualité

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected RBP4 in 10 µg of human liver tissue lysate.

Description de la cible

~23 kDa observed

Liaison

Replaces: MABN1095

Forme physique

Affinity purified

Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable