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Merck
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Key Documents

AB5745

Sigma-Aldrich

Anti-Opsin Antibody, Red/Green

Chemicon®, from chicken

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

chicken

Niveau de qualité

100

Forme d'anticorps

affinity purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

rat, mouse

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
western blot: suitable

Numéro d'accès NCBI

NM_020061.3

Numéro d'accès UniProt

P04000

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Spécificité

Opsin, red and green. The antibody reacts with a protein of ~40 kDa.
Other species have not been tested. It is expected that the antibody will also react with zebra finch.

Immunogène

Synthetic peptides from mouse green opsin and zebra finch red opsin.

Application

Detect Opsin using this Anti-Opsin Antibody, Red/Green validated for use in ELISA & WB.
Immunoblotting: 1:500:1:2,000 on mouse brain extract. To minimize background staining it is suggested that you include a higher content of detergent (Tween-20) in your dilution and washing solutions.

Immunohistochemistry: not tested. It is recommended that you try the antibody at 1:50-1:1,000.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Sensory & PNS

Forme physique

Affinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.
Roberts, MR; Hendrickson, A; McGuire, CR; Reh, TA
Investigative Ophthalmology & Visual Science null
Huirong Li et al.
Molecular neurodegeneration, 16(1), 16-16 (2021-03-12)
Oxidative stress is a common cause of neurodegeneration and plays a central role in retinal degenerative diseases. Heme oxygenase-1 (HMOX1) is a redox-regulated enzyme that is induced in neurodegenerative diseases and acts against oxidative stress but can also promote cell
Patrick W Keeley et al.
Developmental biology, 394(2), 191-196 (2014-08-30)
Programmed cell death contributes to the histogenesis of the nervous system, and is believed to be modulated through the sustaining effects of afferents and targets during the period of synaptogenesis. Cone bipolar cells undergo programmed cell death during development, and

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