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AB1555

Sigma-Aldrich

Anti-NMDAR2A Antibody

serum, Chemicon®

Synonyme(s) :

Anti-EPND, Anti-GluN2A, Anti-LKS, Anti-NMDAR2A, Anti-NR2A

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

serum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

fish, human, rat, mouse

Fabricant/nom de marque

Chemicon®

Technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

Adéquation

not suitable for immunohistochemistry

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... GRIN2A(2903)

Spécificité

NMDAR2A. By Western blot it recognizes a 180 kDa band in rat brain membranes.

Immunogène

C-Terminal Fusion Protein of the NMDAR2A (30 kDa), aa 1253-1391.

Application

Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-NMDAR2A Antibody is validated for use in IP, WB for the detection of NMDAR2A.
Western blotting*: 1:1,000-1:5,000 for ECL. If using labled protein-A for detection: 1:200.

* See suggested protocol

Immunoprecipitation using solubilized hippocampal slices. 3μL will (under appropriate conditions) quantitatively immunoprecipitate all NMDAR2A in 200μg rat brain.

Not suggested for use in immunohistochemistry.

Optimal working dilutions must be determined by the end user.

Forme physique

Rabbit antiserum. Liquid, no preservatives.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles.

Remarque sur l'analyse

Control
NMDAR2A is present in high concentrations in the hippocampus

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

An antisense construct reduces N-methyl-D-aspartate receptor 2A expression and receptor-mediated excitotoxicity as determined by a novel flow cytometric approach.
Pierre A Mattar, Kevin D Holmes, Gregory A Dekaban
Journal of Neuroscience Research null
Differential expression of NMDA and AMPA receptor subunits in rat dorsal and ventral hippocampus.
C Pandis, E Sotiriou, E Kouvaras, E Asprodini, C Papatheodoropoulos, F Angelatou
Neuroscience null
Brain-derived neurotrophic factor and basic fibroblast growth factor downregulate NMDA receptor function in cerebellar granule cells.
C Brandoli, A Sanna, M A De Bernardi, P Follesa, G Brooker, I Mocchetti
The Journal of Neuroscience null
Effects of repeated prenatal glucocorticoid exposure on long-term potentiation in the juvenile guinea-pig hippocampus.
Setiawan, E; Jackson, MF; MacDonald, JF; Matthews, SG
The Journal of Physiology null
Y Honse et al.
Neuroscience, 122(3), 689-698 (2003-11-19)
N-methyl-D-aspartate receptor dysfunction has been strongly suggested to link with the abnormalities seen in fetal alcohol syndrome. Thus, the effects of prenatal ethanol exposure on the total expression of NR1 splice variants and the cell surface expression of both NR1

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