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05-753

Sigma-Aldrich

Anti-WT1 Antibody, clone 6F-H2

clone 6F-H2, Upstate®, from mouse

Synonyme(s) :

Anti-AWT1, Anti-GUD, Anti-NPHS4, Anti-WAGR, Anti-WIT-2, Anti-WT-1, Anti-WT33

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

6F-H2, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Upstate®

Technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

Isotype

IgG1

Numéro d'accès NCBI

NM_024426

Numéro d'accès UniProt

P19544

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... WT1(7490)

Spécificité

WT1

Immunogène

6His-tagged fusion protein corresponding to residues 1-181 of human WT1 (Wilms tumor)

Application

Anti-WT1 Antibody, clone 6F-H2 is a Mouse Monoclonal Antibody for detection of WT1 also known as Wilms′ Tumor & has been tested in WB, ICC & IHC.

Qualité

routinely evaluated by immunoblot on RIPA lysates from Jurkat and Raji cells

Description de la cible

55-60kDa

Forme physique

Format: Purified

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Tarif

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

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Toru Sakairi et al.
American journal of physiology. Renal physiology, 298(3), F557-F567 (2009-12-04)
Evidence suggests that loss of podocytes into urine contributes to development of glomerular diseases; shed podocytes are frequently viable and proliferate in culture conditions. To determine the phenotypic characteristics of viable urinary cells derived from human subjects, we established long-term
Zenglai Tan et al.
Scientific reports, 8(1), 16618-16618 (2018-11-11)
The kidney is a complex organ that is comprised of thousands of nephrons developing through reciprocal inductive interactions between metanephric mesenchyme (MM) and ureteric bud (UB). The MM undergoes mesenchymal to epithelial transition (MET) in response to the signaling from
Toru Sakairi et al.
American journal of physiology. Renal physiology, 299(4), F802-F809 (2010-07-30)
We transformed mouse podocytes by ectopic expression of cyclin-dependent kinase 4 (CDK4). Compared with podocytes transformed with a thermo-sensitive SV40 large T antigen mutant tsA58U19 (tsT podocytes), podocytes transformed with CDK4 (CDK4 podocytes) exhibited significantly higher expression of nephrin mRNA.
Rosalba Parenti et al.
PloS one, 9(12), e114333-e114333 (2014-12-05)
Wilms' tumor gene 1 (WT1) plays complex roles in tumorigenesis, acting as tumor suppressor gene or an oncogene depending on the cellular context. WT1 expression has been variably reported in both benign and malignant peripheral nerve sheath tumors (MPNSTs) by
Aleksandra Rak-Raszewska et al.
Developmental dynamics : an official publication of the American Association of Anatomists (2021-09-09)
Tissue organoids derived from primary cells have high potential for studying organ development and diseases in numerous organs. They recreate the morphological structure and mimic the functions of given organ while being compact in size, easy to produce, and suitable
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