850103P

17:1 Lyso PI

1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt), powder

• Synonyme(s) : PI(17:1(10Z)/0:0); 110718
• Formule empirique (notation de Hill): C₂₆H₅₂NO₁₂P
• Numéro CAS: 1246353-39-8
• Poids moléculaire : 601.66
• Code UNSPSC : 51191904
• Nomenclature NACRES : NA.25

Propriétés

• Pureté: >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 100 μg (with stopper and crimp cap (850103P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850103P-500ug))
• Fabricant/nom de marque: Avanti Polar Lipids 850103P
• Type de lipide: phosphoglycerides
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCC/C=C\CCCCCC)=O.[NH4+]

Description

Description générale

Lysophosphatidylinositol (LPI), a degradation product of phosphatidylinositol (PI) is a lysophospholipid subspecies, which carries inositol in its head group.

Application

17:1 Lyso PI (1-(10Z-heptadecenoyl)-2-hydroxy-sn-glycero-3-phospho-(1′-myo-inositol)) has been used as an internal standard in LC-MS of mice brain lipidomic analysis. It may be used as internal standard in for the analysis of lysophosphatidylinositols (LPIs) in mice using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS) and in the quantification of lysoPI (LPI) in livers of chronic high-fat diet (HFD)-fed WT and KO mice using liquid chromatography with tandem mass spectrometry (LC-MS-MS) system.

Actions biochimiques/physiologiques

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.

Lysophosphatidylinositol (LPI) serve as a bioactive lysophospholipid mediator. It favors mitogenic activity in quiescent fibroblasts. LPI has the ability to block hippocampal neuronal death in conditions of forebrain ischemia.

Conditionnement

2 mL Amber Serum Vial with Stopper and Crimp Cap (850103P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850103P-500ug)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): No data available
• Point d'éclair (°C): No data available