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840858P

Avanti

16:0-18:2 PA

1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate (sodium salt), powder

Synonyme(s) :

1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate (sodium salt); PA(16:0/18:2(9Z,12Z))

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About This Item

Formule empirique (notation de Hill):
C37H68O8PNa
Numéro CAS:
322647-59-6
Poids moléculaire :
694.89
Code UNSPSC :
51191904
Nomenclature NACRES :
NA.25

Pureté

>99% (TLC)

Forme

powder

Conditionnement

pkg of 1 × 100 mg (840858P-100mg)
pkg of 1 × 25 mg (840858P-25mg)

Fabricant/nom de marque

Avanti Polar Lipids 840858P

Type de lipide

phospholipids
cardiolipins

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C37H69O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35H,3-10,12,14-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b13-11-,18-17-;/t35-;/m1./s1

Clé InChI

IYNPOFCKGPJAFU-HQFKUYMNSA-M

Catégories apparentées

Description générale

Phosphatidic acid (PA) is an anionic, membrane structural lipid. It is amphipathic in nature containing a polar head group and two long hydrophobic acyl chains. PA acts as a parent compound for more complex membrane phospholipids. 16:0-18:2 PA or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate is a sodium salt of phosphatidic acid, with substitution of palmitic acid and linolenic acid at the sn-1 and sn-2 positions respectively, in the glycerol backbone.

Application

16:0-18:2 PA or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate (sodium salt) might be used as a standard in thin-layer chromatography (TLC) for the separation of ginger and grapefruit exosome-like nanoparticles (ELN)-derived lipids. It might also be used in filter-blotting assay, to study the interaction of AT-hook motif-containing nuclear localized protein 4 (Ahl4) with PA.

Actions biochimiques/physiologiques

Phosphatidic acid (PA) is a bioactive lipid and acts as a secondary messenger. It is associated with hydrogen peroxide production in the neutrophils. PA stimulates the action of protein kinase for neutrophil respiratory burst. It also participates in Ras mediated signaling pathways. PA reacts with water and other phospholipids to produce lipid bilayers and multicomponent bilayers respectively.

Conditionnement

5 mL Clear Glass Sealed Ampule (840858P-100mg)
5 mL Clear Glass Sealed Ampule (840858P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Lipid second messengers and Receptors
Encyclopedia of Endocrine Diseases, 77(3), 329-334 (2004)
Guangqin Cai et al.
Molecular plant, 13(7), 984-1000 (2020-04-26)
Lipid catabolism in germinating seeds provides energy and substrates for initial seedling growth, but how this process is regulated is not well understood. Here, we show that an AT-hook motif-containing nuclear localized (AHL) protein regulates lipid mobilization and fatty acid
Yun Teng et al.
Cell host & microbe, 24(5), 637-652 (2018-11-20)
The gut microbiota can be altered by dietary interventions to prevent and treat various diseases. However, the mechanisms by which food products modulate commensals remain largely unknown. We demonstrate that plant-derived exosome-like nanoparticles (ELNs) are taken up by the gut

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