700001P

DC-Cholesterol HCl

Avanti Research^™ - A Croda Brand 700001P, powder

• Synonyme(s) : 3β-[N-(N′,N′-dimethylaminoethane)-carbamoyl]cholesterol hydrochloride
• Formule empirique (notation de Hill): C₃₂H₅₇N₂O₂Cl
• Numéro CAS: 166023-21-8
• Poids moléculaire : 537.26
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Pureté: >99% (TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 1 g (700001P-1g); pkg of 1 × 200 mg (700001P-200mg); pkg of 1 × 25 mg (700001P-25mg); pkg of 1 × 500 mg (700001P-500mg)
• Fabricant/nom de marque: Avanti Research^™ - A Croda Brand 700001P
• Application(s): vaccine development
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Chaîne SMILES: [H][C@](C1)(OC(NCC[N+](C)([H])C)=O)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@@H](C)CCCC(C)C.[Cl-]
• InChI: 1S/C32H56N2O2.ClH/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5;/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35);1H
• Clé InChI: ISXSJGHXHUZXNF-UHFFFAOYSA-N

Description

Description générale

DC-Cholesterol HCl is a cholesterol derivative and a cationic lipid with a head group and linker moiety.

DC-Cholesterol HCl is a sterol-based transfection reagent.

Application

DC-Cholesterol HCl is suitable:

• for the preparation of ultrasound cationic microbubbles
• to prepare liposomes
• for the preparation of L-glutathione (GSH), loaded proliposomes

DC-Cholesterol HCl may be used in the preparation of colloidal dispersions for transmission electron microscopy studies. It may also be used in liposome preparation for assessing hexokinase activity, poly (lactic-coglycolicacid) loading and in mRNA transfection studies.

Actions biochimiques/physiologiques

DC-Cholesterol is an effective transfection agent and a liposome reagent. Liposome of DC-Cholesterol with dioleoylphosphatidylethanolamine (DOPE) are efficient for DNA transfection. It imparts positive surface charge to the microbubbles for ultra sound based transfection of clustered regularly interspaced short palindromic repeats (CRISPRs).

DC-cholesterol is a cationic lipid, known to be the most efficient in gene transfection study.

Conditionnement

20 mL Clear Glass Screw Cap Vial (700001P-1g)

20 mL Clear Glass Screw Cap Vial (700001P-500mg)

5 mL Amber Glass Screw Cap Vial (700001P-200mg)

5 mL Amber Glass Screw Cap Vial (700001P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable