QBD10211

m-dPEG^®₄-NHS ester

• Synonyme(s) : 2,5-Dioxo-1-pyrrolidinyl 4,7,10,13-tetraoxatetradecanoate, Polyethylene glycol, Triethylene glycol methyl ether 2-(succinimidyloxycarbonyl)ethyl ether
• Formule empirique (notation de Hill): C₁₄H₂₃NO₈
• Numéro CAS: 622405-78-1
• Poids moléculaire : 333.33
• Numéro MDL: MFCD11041112
• Code UNSPSC : 12352108
• ID de substance PubChem : 329823894
• Nomenclature NACRES : NA.22

Propriétés

• Pureté: >90%
• Forme: solid or viscous liquid
• Pertinence de la réaction: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• Architecture des polymères: shape: linear; functionality: monofunctional
• Conditions d'expédition: ambient
• Température de stockage: −20°C
• Chaîne SMILES: O=C1CCC(N1OC(CCOCCOCCOCCOC)=O)=O
• InChI: 1S/C14H23NO8/c1-19-6-7-21-10-11-22-9-8-20-5-4-14(18)23-15-12(16)2-3-13(15)17/h2-11H2,1H3
• Clé InChI: MAYFFZZPEREGBQ-UHFFFAOYSA-N

Description

Caractéristiques et avantages

The m-dPEG^®₄-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₄-NHS (N-hydroxysuccinimide) ester reacts with amines.

Informations légales

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable