CPGG-501

Anionic PEGylated Liposomes

DSPC:Chol:DSPG:DSPE-PEG(2000) (60:30:5:5 molar ratio 10mM)

• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Niveau de qualité: 100
• Composition: Phosphate buffered saline
• Concentration: 10 mM
• Impuretés: 30 mol % Cholesterol ; 5 mol % DSPE-PEG2000; 5 mol % DSPG; 60 mol % DSPC
• Taille des particules: 100 nm
• pH: 7.4

Description

Description générale

Poly(ethylene glycol) (PEG) is commonly added to liposomes to improve stability, hydrophilicity and enhance circulation time. Anionic PEGylated liposomes protect liposomes from circulating proteins, improving their plasma clearance and enhancing their therapeutic effects. In addition, anionic liposomes demonstrate greater stability in solution, lead to lower aggregation when compared to neutral liposomes, and have increased endocytosis when compared with cationic and neutral liposomes.

Application

Drug delivery
Lipid-protein interactions

Stockage et stabilité

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

Informations légales

Cellsome is a trademark of Encapsula NanoSciences

Product of Encapsula Nanosciences

Clause de non-responsabilité

For research use only

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable