931853

SPhos Pd G6 acylation

≥95%

• Synonyme(s) : (SPhos)Pd(4-CH₂CH₂CONHSPh)Br
• Formule empirique (notation de Hill) : C₃₉H₄₇BrNO₆PPd
• Numéro CAS: 2723495-97-2
• Poids moléculaire : 843.09
• Numéro MDL: MFCD34704619
• Code UNSPSC : 12352100
• Nomenclature NACRES : NA.21

Propriétés

• Niveau de qualité: 100
• Essai: ≥95%
• Forme: powder
• Pertinence de la réaction: reagent type: catalyst; reaction type: Cross Couplings
• Caractéristiques du produit alternatif plus écologique: Catalysis; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• Autre catégorie plus écologique: Aligned

Description

Description générale

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product has been enhanced for catalytic efficiency. Click here for more information.

Application

SPhos Pd G6 acylation is an oxidative addition complex (OAC) of SPhos for use in bioconjugation. The pendant NHS-functional group allows coupling to protein amines through a selective acylation. The protein-OAC can then be reacted with a second, cysteine-containing protein. This facile approach allows for protein homodimerization as well as the formation of antibody-protein conjugates.

Learn more about G6 Buchwald precatalysts

Autres remarques

Palladium–Protein Oxidative Addition Complexes by Amine-Selective Acylation

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable