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Merck
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Key Documents

921793

Sigma-Aldrich

Rhombic chamber chip - 100 μl

Fluidic 221, PMMA

Synonyme(s) :

Microfluidic, Microparticle, Nanoparticle

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About This Item

Description

Microfludic chip x1

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Application

Chamber chips come in the format of a microscopy slide (75.5 mm x 25.5 mm x 1.5 mm) and are equipped with Mini Luer interfaces. Their key microfluidic elements are reaction chambers of various volumes. Chamber chips are the perfect tool to facilitate reactions, such as amplification of a targeted DNA during qPCR, or to extract target molecules out of a given sample in preparative quantities. These chips can, for example, be used as nucleic acid extraction devices via magnetic beads simply via applying beads and sample and by using an external magnet to hold the beads in place. These procedures can be done completely manually with a pipette – besides the magnet no additional equipment is necessary – or semi-automated with normal peristaltic pumps found in most life science labs.

Rhombic chamber chip - 100 μl, Fluidic 221, PMMA is made of PMMA (Poly(methyl methacrylate)) and offers rhombic chambers with two inlets and two outlets. These chips are versatile tools for various experimental procedures such as sample preparation.

Chip Properties:
  • Orientation: Lengthwise
  • Mini Luer Interface
  • Material: Poly(methyl methacrylate) (PMMA)
  • Chamber Volume: 100μl
  • Chamber Depth: 600μm

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Recent advances of controlled drug delivery using microfluidic platforms.
Li X, et al.
Advanced Drug Delivery Reviews, 128, 3-28 (2018)
Microfluidic-assisted fabrication of carriers for controlled drug delivery.
Santos H A, et al.
Lab on a chip, 17, 1856-1883 (2017)
Sharma T Sanjay et al.
Advanced drug delivery reviews, 128, 3-28 (2017-09-19)
Conventional systematically-administered drugs distribute evenly throughout the body, get degraded and excreted rapidly while crossing many biological barriers, leaving minimum amounts of the drugs at pathological sites. Controlled drug delivery aims to deliver drugs to the target sites at desired
Dongfei Liu et al.
Lab on a chip, 17(11), 1856-1883 (2017-05-10)
The microfluidic technique has brought unique opportunities toward the full control over the production processes for drug delivery carriers, owing to the miniaturisation of the fluidic environment. In comparison to the conventional batch methods, the microfluidic setup provides a range

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