718742

BrettPhos

98%

• Synonyme(s) : 2-(Dicyclohexylphosphino)3,6-dimethoxy-2′,4′,6′-triisopropyl-1,1′-biphenyl
• Formule empirique (notation de Hill): C₃₅H₅₃O₂P
• Numéro CAS: 1070663-78-3
• Poids moléculaire : 536.77
• Numéro MDL: MFCD11973797
• Code UNSPSC : 12352112
• ID de substance PubChem : 329763602
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 300
• Pureté: 98%
• Forme: solid
• Capacité de réaction: reaction type: Cross Couplings
• Pertinence de la réaction: reagent type: ligand; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reagent type: ligand; reaction type: Fluorinations
• Score du produit alternatif plus écologique: old score: 8; new score: 1; Find out more about DOZN™ Scoring
• Caractéristiques du produit alternatif plus écologique: Waste Prevention; Atom Economy; Design for Energy Efficiency; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• Pf: 187-195 °C
• Groupe fonctionnel: phosphine
• Autre catégorie plus écologique: , Re-engineered
• Chaîne SMILES: COc1c(P(C2CCCCC2)C3CCCCC3)c(c4c(C(C)C)cc(C(C)C)cc4C(C)C)c(OC)cc1
• InChI: 1S/C35H53O2P/c1-23(2)26-21-29(24(3)4)33(30(22-26)25(5)6)34-31(36-7)19-20-32(37-8)35(34)38(27-15-11-9-12-16-27)28-17-13-10-14-18-28/h19-25,27-28H,9-18H2,1-8H3
• Clé InChI: WDVGNXKCFBOKDF-UHFFFAOYSA-N

Description

Description générale

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Atom Economy” and “Design for Energy Efficiency”. Click here to view its DOZN scorecard.

Application

Buchwald Phosphine Ligands for chemical Synthesis

BrettPhos is a dialkylbiaryl phosphine ligand developed by the Buchwald group. It promotes cross-coupling reactions more efficiently and exhibits improved reactivity compared to other catalytic systems.
It can be used in:

• palladium-catalyzed trifluoromethylation of aryl chlorides
• Buchwald-Hartwig amination
• synthesis of 4-aryl and alkyl substituted, N⁶-alkylated pyridazine-3,6-diamines via a Buchwald protocol

For small scale and high throughput uses, product is also available as ChemBeads (928348)

Caractéristiques et avantages

• White crystalline solid
• Air- and moisture-stable
• Thermally stable
• Highly efficient
• Wide functional group tolerance
• Excellent selectivity and conversion

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable