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376914

Sigma-Aldrich

Poly(methyl methacrylate-co-methacrylic acid)

average Mw ~34,000 by GPC, average Mn ~15,000 by GPC

Synonyme(s) :

Poly(methacrylic acid-co-methyl methacrylate)

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About This Item

Numéro CAS:
25086-15-1
Numéro MDL:
MFCD00243185
Code UNSPSC :
12162002
ID de substance PubChem :
24863477
Nomenclature NACRES :
NA.23

Ratio alimentaire

1:0.016 (methyl methacrylate:methacrylic acid)

Poids mol.

average Mn ~15,000 by GPC
average Mw ~34,000 by GPC

Viscosité inhérente

0.19 dL/g(lit.)

Température de transition

Tg 105 °C

InChI

1S/C5H8O2.C4H6O2/c1-4(2)5(6)7-3;1-3(2)4(5)6/h1H2,2-3H3;1H2,2H3,(H,5,6)

Clé InChI

IWVKTOUOPHGZRX-UHFFFAOYSA-N

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Application

  • Ultrafine Nanoparticles of Poly(Methyl Methacrylate-co-Methacrylic Acid) Loaded with Aspirin: This study focuses on the preparation and potential therapeutic applications of biocompatible nanoparticles loaded with aspirin, highlighting their suitability for medical use (López-Muñoz et al., 2019).
  • Biocompatible and biodegradable ultrafine nanoparticles of poly (methyl methacrylate-co-methacrylic acid) prepared via semicontinuous heterophase: Discusses the synthesis of biodegradable nanoparticles for potential biomedical applications, emphasizing their eco-friendly nature and suitability for drug delivery systems (Saade et al., 2016).
  • Synthesis and characteristics of poly(methyl methacrylate‐co‐methacrylic acid)/poly(methacrylic acid‐co‐N‐isopropylacrylamide) thermosensitive semi‐hollow latex: Explores the unique properties of thermosensitive latex particles for advanced material applications, potentially useful in smart drug delivery systems (Lee et al., 2014).
  • Preparation and release behavior of poly(methyl methacrylate-co-methacrylic acid)-based electrospun nanofibrous mats loaded with doxorubicin: Examines the use of polymeric nanofibers for controlled drug release, particularly for cancer treatment, demonstrating the versatility of poly(methyl methacrylate-co-methacrylic acid) in pharmaceutical applications (López-Muñoz et al., 2023).

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
MKBG3620V
MKBG3616V
MKBD4926
MKBD4927
02414EJ

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Sigma-Aldrich

463183

Poly(methyl methacrylate-co-ethylene glycol dimethacrylate)

Martins Emeje et al.
Acta pharmaceutica (Zagreb, Croatia), 62(1), 71-82 (2012-04-05)
Sustained release (SR) dosage forms enable prolonged and continuous deposition of the drug in the gastrointestinal (GI) tract and improve the bioavailability of medications characterized by a narrow absorption window. In this study, a new strategy is proposed for the
Suprita A Tawde et al.
Vaccine, 30(38), 5675-5681 (2012-07-04)
Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US. Customized immunotherapeutic strategies may serve as an alternative method to control the recurrence or progression of ovarian cancer and to avoid severe adverse
Pravin K Pawar et al.
Acta pharmaceutica (Zagreb, Croatia), 62(1), 93-104 (2012-04-05)
The objective of the present investigation was to prepare and evaluate ocular inserts of moxifloxacin. An ocular insert was made from an aqueous dispersion of moxifloxacin, sodium alginate, polyvinyl alcohol, and dibutyl phthalate by the film casting method. The ocular
Prathap Nagaraja Shastri et al.
Drug development and industrial pharmacy, 39(2), 164-175 (2012-05-18)
Oral delivery of proteins has been a challenging as well as rapidly developing field. To implement mixture design of experiment to develop enteric-coated microparticles containing bovine serum albumin. Microparticles were prepared using Buchi Spray Dryer 191. Simplex lattice mixture design
Yan Zhang et al.
International journal of pharmaceutics, 436(1-2), 341-350 (2012-07-07)
In the present study thiolated Eudragit L100 (Eul) based polymeric nanoparticles (NPs) were employed to develop an oral insulin delivery system. Sulfydryl modification was achieved by grafting cysteine to the carboxylic acid group of Eudragit L100, which displayed maximum conjugate
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