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Merck

SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Synonymes:
ASV, SRC1, c-SRC, p60-Src
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene

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Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Acide phosphorique, ACS reagent, ≥85 wt. % in H2O,
Espèce(s)
human
Acide phosphorique, 85 wt. % in H2O, 99.99% trace metals basis,
Espèce(s)
human
Acide phosphorique, ACS reagent, ≥85 wt. % in H2O,
Espèce(s)
human
Acide phosphorique, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥85%,
Espèce(s)
human
Acide citrique, ACS reagent, ≥99.5%,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anticorps anti-phospho-Src (Tyr416), clone 9A6, clone 9A6, Upstate®, from mouse,
Espèces réactives
human, mouse
Application
immunoprecipitation (IP)
western blot
Anti-phospho-Src (Tyr418) Antibody, Upstate®, from rabbit,
Espèces réactives
chicken, human, mouse
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-SRC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
western blot
Anti-Phospho-Src-Y419 antibody produced in rabbit, ,
Espèces réactives
human, mouse
Application
western blot
Anti-phospho-SRC (pTyr529) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
SU 6656, ≥98% (HPLC),
Espèce(s)
human
Radicicol from Diheterospora chlamydosporia, solid,
Espèce(s)
human, rat
Ellagic acid, ≥95% (HPLC), powder, from tree bark,
Espèce(s)
human, rat
Tyrphostin A9, solid,
Espèce(s)
mouse, human
Dasatinib, ≥98% (HPLC),
Espèce(s)
human

Kits

Référence du produit
Description
Espèce(s)
Src Kinase Reaction Buffer, ,
Espèce(s)
human

Proteins

Référence du produit
Description
Espèce(s)
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Espèce(s)
human
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Espèce(s)
human
SRC N1 human, ≥60% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Espèce(s)
human
Src Manganese/ATP Cocktail, ,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Src,
Espèce(s)
mouse

Small Molecule - Substrate

Référence du produit
Description
Espèce(s)
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Espèce(s)
human