ESR1

estrogen receptor 1

Synonymes:

ER, ESR, ESRA, ESTRR, Era, NR3A1

Espèce(s):

Human ESR1 (2099), Mouse Esr1 (13982), Rat Esr1 (24890), Goat ESR1 (100860768), sheep ESR1 (443228), domestic guinea pig Esr1 (100713276), Zebrafish esr1 (259252), dog ESR1 (403640), cow ESR1 (407238), Horse ESR1 (791249) ...Plus

ID UniProtKB:

P03372, Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7

ID du gène:

Human(2099) Summary: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
Mouse(13982) estrogen receptor 1 (alpha)
Rat(24890) estrogen receptor 1
Goat(100860768) estrogen receptor 1
sheep(443228) estrogen receptor 1
domestic guinea pig(100713276) estrogen receptor 1
Zebrafish(259252) estrogen receptor 1
dog(403640) estrogen receptor 1
cow(407238) estrogen receptor 1
Horse(791249) estrogen receptor 1
domestic cat(552888) estrogen receptor 1
chicken(396099) estrogen receptor 1
Thale Cress(837856) ethylene-responsive transcription factor ESR1

Produits (195)
Articles revus par des pairs (901)

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Small Molecule - Activator

Référence du produit

Description

Espèce(s)

131083

4-Phenylazophenol, 98%,

Espèce(s)

human

N0632

β-Nicotinamide-adénine-dinucléotide sodium salt, ,

Espèce(s)

human

N7004

β-Nicotinamide-adénine-dinucléotide hydrate, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,

Espèce(s)

human

139939

trans-Stilbene, 96%,

Espèce(s)

human, rat

43410

β-Nicotinamide-adénine-dinucléotide hydrate, ≥95% (HPLC),

Espèce(s)

human

Small Molecule - Agonist

Référence du produit

Description

Espèce(s)

E-060

17β-Estradiol solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®,

Espèce(s)

human

1250008

β-Estradiol, United States Pharmacopeia (USP) Reference Standard,

Espèce(s)

human

PHR1353

β-Estradiol, Pharmaceutical Secondary Standard; Certified Reference Material,

Espèce(s)

human

E-075

Estrone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®,

Espèce(s)

human

1260001

17α-Ethynylestradiol, United States Pharmacopeia (USP) Reference Standard,

Espèce(s)

human

Small Molecule - Allosteric Modulator

Référence du produit

Description

Espèce(s)

85256

Tamoxifène, analytical standard,

Espèce(s)

human

1643306

Tamoxifen citrate, United States Pharmacopeia (USP) Reference Standard,

Espèce(s)

human

06734

Tamoxifène, certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,

Espèce(s)

human

BP1225

Tamoxifen citrate, British Pharmacopoeia (BP) Reference Standard,

Espèce(s)

human

T0014000

Tamoxifen citrate, European Pharmacopoeia (EP) Reference Standard,

Espèce(s)

human

Small Molecule - Antagonist

Référence du produit

Description

Espèce(s)

524980

Dibutyl phthalate, 99%,

Espèce(s)

mouse

308501

Benzyl butyl phthalate, 98%,

Espèce(s)

mouse

Z2125

Zearalenone, fungal mycotoxin,

Espèce(s)

mouse

290823

4-tert-Octylphenol, 97%,

Espèce(s)

mouse

49085

Atrazine, analytical standard,

Espèce(s)

mouse

Antibodies

Référence du produit

Description

Espèces réactives

Application

HPA000449

Anti-ESR1 antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,

Espèces réactives

human

Application

immunofluorescence
immunohistochemistry
western blot

SAB4500813

Anti-Estrogen Receptor-α antibody produced in rabbit, affinity isolated antibody,

Espèces réactives

human

Application

ELISA
immunohistochemistry
western blot

04-1564

Anti-Estrogen Receptor α Antibody, clone F3-A, ascites fluid, clone F3-A, from mouse,

Espèces réactives

human, mouse, rat

Application

immunocytochemistry
western blot

AMAB90867

Monoclonal Anti-ESR1 antibody produced in mouse, Prestige Antibodies^® Powered by Atlas Antibodies, clone CL1196, purified immunoglobulin, buffered aqueous glycerol solution,

Espèces réactives

human

Application

immunofluorescence
immunohistochemistry
western blot

07-662

Anti-Estrogen-related Receptor α Antibody, Upstate^®, from rabbit,

Espèces réactives

hamster, human, mouse, rat

Application

electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot