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Merck

CRTC2

CREB regulated transcription coactivator 2

Synonymes:
TORC-2, TORC2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(200186) Summary: This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]
  • Mouse(74343) CREB regulated transcription coactivator 2
  • Rat(310615) CREB regulated transcription coactivator 2
  • domestic guinea pig(100727423) CREB regulated transcription coactivator 2
  • naked mole-rat(101709168) CREB regulated transcription coactivator 2
  • sheep(101102117) CREB regulated transcription coactivator 2
  • cow(540959) CREB regulated transcription coactivator 2
  • Horse(100056571) CREB regulated transcription coactivator 2
  • domestic cat(101101104) CREB regulated transcription coactivator 2
  • dog(612305) CREB regulated transcription coactivator 2

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CRTC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CRTC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-CRTC2 Antibody, clone 5B10, ascites fluid, clone 5B10, from mouse,
Espèces réactives
human
Application
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Monoclonal Anti-CRTC2 antibody produced in mouse, clone 1E6, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
western blot
Anti-CRTC2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
mouse, rat
Application
ELISA
western blot

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human CRTC2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Crtc2,
Espèce(s)
mouse