BAX
BCL2-associated X protein
Synonymes:
BCL2L4
Espèce(s):
Human BAX (581), Mouse Bax (12028), Rat Bax (24887), naked mole-rat Bax (101713575), domestic guinea pig Bax (100730890), Goat BAX (100846984), sheep BAX (443059), dog BAX (403523), domestic cat BAX (493837), cow BAX (280730)
ID UniProtKB:
ID du gène:
- Human(581) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12028) BCL2-associated X protein
- Rat(24887) Bcl2-associated X protein
- naked mole-rat(101713575) BCL2-associated X protein
- domestic guinea pig(100730890) BCL2-associated X protein
- Goat(100846984) BCL2-associated X protein
- sheep(443059) BCL2-associated X protein
- dog(403523) BCL2-associated X protein
- domestic cat(493837) BCL2-associated X protein
- cow(280730) BCL2-associated X protein
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Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-Bax (NT) Antibody, from rabbit,
Espèces réactives
bovine, canine, chimpanzee, feline, human, rhesus monkey
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Bax Antibody, NT, aa3-16 hBax protein, clone 2D2, clone 2D2, Chemicon®, from mouse,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Bax Antibody, clone 1C7, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-BAX antibody produced in rabbit, ,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Monoclonal Anti-BAX antibody produced in mouse, clone 1F5-1B7, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
Cell Lines
Proteins
Référence du produit
Description
Espèce(s)
BAX, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human
esiRNA
Référence du produit
Description
Espèce(s)