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Key Documents

SAB1300696

Sigma-Aldrich

Anti-OIT3(L) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-LZP, Anti-Liver-specific zona pellucida domain-containing protein, Anti-OIT3, Anti-Oncoprotein-induced transcript 3 protein [Precursor]

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI accession no.

NP_689848

UniProt accession no.

Q8WWZ8

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... OIT3(170392)

General description

Liver-specific ZP domain-containing protein (OIT3) is a liver-specific protein involved possibly in hepatocellular function and development. Oncoprotein induced transcript 3 (OIT3) is also known as liver-specific zona pellucida domain-containing protein and is composed of 545 amino acid residues. It is expressed in the liver and secreted into the blood. OIT3 possesses a D8C (domain with conserved eight cysteines) domain, an amino-terminal signal peptide and three epidermal growth factor (EGF)-like domains. The cDNA of the protein consists of 2,255bp. The gene encoding OIT3 is localized on human chromosome 10q21.3, spans 40kb and has nine exons.

Immunogen

OIT3 (NP_689848, )
This antibody is generated from rabbits immunized with a GST tag human OIT3 recombinant protein.

Biochem/physiol Actions

Oncoprotein induced transcript 3 (OIT3) may have a role in liver development and function. It has been shown to be downregulated in hepatocellular carcinoma.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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