S9399

Staphylococcal enterotoxin A from Staphylococcus aureus

• CAS Number: 642595-84-4
• MDL number: MFCD00082015
• UNSPSC Code: 12352200

Properties

• contains: sodium phosphate buffer as balance
• Quality Level: 200
• composition: Protein, ~10% Lowry
• availability: not available in USA
• impurities: Staphylococcal enterotoxin B (SEB), essentially free
• solubility: H₂O: complete 1 mg/ml, clear, colorless
• storage temp.: 2-8°C

Description

General description

Staphylococcal enterotoxin A belongs to the family of staphylococcal exotoxins. It is secreted by Staphylococcus aureus, a Gram-positive bacteria.

Application

Staphylococcal enterotoxin A from Staphylococcal aureus was injected peritoneally in mice to induce sepsis.¹⁰

Staphylococcal enterotoxin A from Staphylococcus aureus has been used as an external standard in for the verification of TRANSIA assay kit, RIDASCREEN assay kit and Vidas Set 2 method. For in vitro toxin stimulation of mouse splenocytes.

Biochem/physiol Actions

Staphylococcal enterotoxin A from Staphylococcus aureus is leading agent that causes of food poisoning. A concentration of as little as 0.5 mg/ml is sufficient to result in nausea, vomiting, diarrhea and cramps.⁸ It stimulates the cell proliferation of peripheral lymphocytes, induces the production of interferons and is important for gut immunity against S. aureus infections.⁹ It acts as a super antigen for T-lymphocytes.

Packaging

Package size based on protein content

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 + H332
• Precautionary Statements: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves