M8890
Anti-Mouse IgG (whole molecule) antibody produced in goat
IgG fraction of antiserum, lyophilized powder
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About This Item
Recommended Products
biological source
goat
Quality Level
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
secondary antibodies
clone
polyclonal
form
lyophilized powder
packaging
vial of 2 mL lyophilized antiserum
technique(s)
Ouchterlony double diffusion: 1:8
storage temp.
2-8°C
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Application
Anti-Mouse IgG (whole molecule) antibody produced in goat was used to immunoprecipitate bovine brain adenylyl cyclase. It was used α-defensin isoforms in the plasma of type I diabetic patients by radio immune assay.
Biochem/physiol Actions
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Physical form
Lyophilized from 0.01 M phosphate buffered saline, pH 7.2
Reconstitution
Reconstitute with 2 mL deionized water.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Certificates of Analysis (COA)
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Gowsini Joseph et al.
The Journal of clinical endocrinology and metabolism, 93(4), 1470-1475 (2008-01-24)
alpha-Defensins are antimicrobial peptides of the innate immune system. In addition, experimental evidence suggests that alpha-defensins are proatherogenic. The objective of the study was to examine the predictive value of plasma alpha-defensin as a clinical marker of cardiovascular disease (CVD)
S Mollner et al.
European journal of biochemistry, 171(1-2), 265-271 (1988-01-15)
Four monoclonal antibodies, raised against the 115-kDa adenylyl cyclase from bovine brain [Pfeuffer, E. et al. (1985) EMBO J. 4, 3675-3679] have been selected and designated BBC-1 to BBC-4. BBC-1 and BBC-3 are highly specific for the 115-kDa enzyme from
Julius Grzeschik et al.
Biotechnology journal, 14(4), e1800466-e1800466 (2018-10-24)
Yeast surface display emerged as a viable tool for the generation of human and murine monoclonal antibodies. This platform technology enables the careful definition of selection conditions, the potential for high-throughput screening, as well as the isolation of antibodies recognizing
L L Peters et al.
Blood, 76(4), 745-754 (1990-08-15)
A new autosomal recessive mouse mutation, scat (severe combined anemia and thrombocytopenia), causes intermittent episodes of severe bleeding in the homozygote. At birth, affected mice are pale with intradermal petechiae and bruises on exposed surfaces. Central nervous system (CNS) bleeding
M Saraheimo et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 23(3), 914-918 (2007-11-16)
Diabetic nephropathy is associated with low-grade inflammation and activation of the complement system. Defensins, as part of the innate immune system, may play a regulatory role in the complement cascade and may also augment the production of proinflammatory cytokines. The
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