E1279

Enoximone

solid

• Synonym(s): 1,3-Dihydro-4-methyl-5-(4-methylthiobenzoyl)-2H-imidazol-2-one
• Empirical Formula (Hill Notation): C₁₂H₁₂N₂O₂S
• CAS Number: 77671-31-9
• Molecular Weight: 248.30
• MDL number: MFCD00867130
• UNSPSC Code: 41106305
• PubChem Substance ID: 24278408
• NACRES: NA.77

Properties

• form: solid
• color: light yellow
• solubility: DMSO: soluble 28 mg/mL
• SMILES string: CSc1ccc(cc1)C(=O)C2=C(C)NC(=O)N2
• InChI: 1S/C12H12N2O2S/c1-7-10(14-12(16)13-7)11(15)8-3-5-9(17-2)6-4-8/h3-6H,1-2H3,(H2,13,14,16)
• InChI key: ZJKNESGOIKRXQY-UHFFFAOYSA-N
• Gene Information: human ... PDE3A(5139) , PDE3B(5140)

Description

Biochem/physiol Actions

Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves