A8056

3-Amino-1,2,4-triazole

≥95% (TLC)

• Synonym(s): 1,2,4-Triazol-3-amine, 3-AT, Amitrol
• Empirical Formula (Hill Notation): C₂H₄N₄
• CAS Number: 61-82-5
• Molecular Weight: 84.08
• Beilstein: 107687
• EC Number: 200-521-5
• MDL number: MFCD00005230
• UNSPSC Code: 12352204
• PubChem Substance ID: 24891312
• NACRES: NA.83

Properties

• biological source: synthetic (organic)
• Quality Level: 200
• Assay: ≥95% (TLC)
• form: powder
• potency: 30 μM K_i
• mp: 150-153 °C (lit.)
• solubility: water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
• storage temp.: −20°C
• SMILES string: Nc1nc[nH]n1
• InChI: 1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)
• InChI key: KLSJWNVTNUYHDU-UHFFFAOYSA-N

Description

General description

3-Amino-1,2,4-triazole is a herbicide effective against weeds especially bermuda and quack grass. It enters plant circulation through roots and is majorly present in the meristem. 3-Amino-1,2,4-triazole inhibits chlorophyll synthesis resulting in chlorotic leaves and albino plants. In addition, it also affects the growth of the plants. It is exploited to destroy unwanted weeds. It is synthesized from aminoguanidine formate and corresponds to a molecular weight of 84 Da.

Application

3-Amino-1,2,4-triazole has been used:

• as an organelle-specific perturbant in human embryonic kidney (HEK293T) cells
• as histidine biosynthesis inhibitor in medium for screening co-transformants from yeast two-hybrid interactions
• for preservation of midgut sample from honey bee
• for the determination of tryptophan in proteins.

Safety Information

• Pictograms: GHS08,GHS09
• Signal Word: Warning
• Hazard Statements: H361d - H373 - H411
• Precautionary Statements: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Hazard Classifications: Aquatic Chronic 2 - Repr. 2 - STOT RE 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves