47729

N-Formyl-Met-Leu-Phe

BioXtra, ≥99.0% (TLC)

• Synonym(s): Chemotactic peptide, N-Formyl-L-methionyl-L-leucyl-L-phenylalanine, fMLF, fMLP (misnomer but widely used)
• Empirical Formula (Hill Notation): C₂₁H₃₁N₃O₅S
• CAS Number: 59880-97-6
• Molecular Weight: 437.55
• Beilstein: 2315783
• MDL number: MFCD00036780
• UNSPSC Code: 12352209
• PubChem Substance ID: 57651094

Properties

• product line: BioXtra
• Quality Level: 100
• Assay: ≥99.0% (TLC)
• form: powder
• color: white
• solubility: DMF: 50 mg/mL, clear, colorless
• application(s): cell analysis
• storage temp.: 2-8°C
• SMILES string: CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
• InChI: 1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1
• InChI key: PRQROPMIIGLWRP-BZSNNMDCSA-N
• Gene Information: human ... FPR1(2357)

Description

Amino Acid Sequence

NFor-Met-Leu-Phe

Application

1. 4th and 5th applications do not have access
2. 3rd application is not relevant

Biochem/physiol Actions

N-Formyl-Met-Leu-Phe is a potent chemotactic peptide and formyl peptide receptor (FPR) agonist that induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.

Potent chemotactic peptide. Induces a metabolic burst in macrophages accompanied by an increase in respiratory rate, secretion of lysosomal enzymes, and production of superoxide anion.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves