306576

Sodium hydroxide

pellets, semiconductor grade, 99.99% trace metals basis

• Synonym(s): ‘Caustic soda’
• Linear Formula: NaOH
• CAS Number: 1310-73-2
• Molecular Weight: 40.00
• EC Number: 215-185-5
• MDL number: MFCD00003548
• UNSPSC Code: 12352316
• PubChem Substance ID: 329753559
• NACRES: NA.21

Properties

• grade: semiconductor grade
• Quality Level: 200
• vapor density: >1 (vs air)
• vapor pressure: <18 mmHg ( 20 °C); 3 mmHg ( 37 °C)
• Assay: 99.99% trace metals basis
• form: pellets
• technique(s): HPLC: suitable
• impurities: <1% Na₂CO₃
• mp: 318 °C (lit.)
• solubility: water: soluble 1,260 g/L at 20 °C
• density: 2.13 g/cm³ at 20 °C
• SMILES string: [OH-].[Na+]
• InChI: 1S/Na.H2O/h;1H2/q+1;/p-1
• InChI key: HEMHJVSKTPXQMS-UHFFFAOYSA-M

Description

General description

Sodium hydroxide (caustic soda, NaOH) is a water-soluble inorganic base with a wide range of industrial applications such as titration methods, dissolution testing, and pH adjusting. It is also used as a precipitant to precipitate transition metal hydroxides.

Application

• Alkaliptosis induction counteracts paclitaxel-resistant ovarian cancer cells: Utilizing sodium hydroxide in ATP6V0D1-mediated ABCB1 inhibition reveals a novel approach to overcoming drug resistance in ovarian cancer, promoting cell death through alkaliptosis. This could significantly impact cancer treatment strategies (Chen et al., 2024).


• Ozone-activated lignocellulose films blended with chitosan: Research shows potential for creating biodegradable, edible films using sodium hydroxide in the activation process. This application is particularly relevant in food packaging and could revolutionize how we approach sustainable material science (Ebrahimi et al., 2024).


• Stabilizing fish oil emulsions with tilapia head gelatins: Investigating the effects of sodium hydroxide in the extraction of gelatins, this study highlights its utility in enhancing the stability and usability of fish oil emulsions in food science (Li et al., 2024).


• Cellulose dissolution in ZnO/NaOH/Water solvent solution: Molecular dynamics simulation studies illustrate how sodium hydroxide aids in dissolving cellulose, with temperature-dependent effects providing insights into polymer science applications, especially in textile and material production (Bourassi et al., 2024).


• Recycling Metakaolin/Slag-Based Geopolymer Concrete: Sodium hydroxide plays a crucial role in developing geopolymer concretes capable of withstanding severe freeze-thaw conditions, suggesting significant applications in sustainable construction materials (Liu et al., 2024).

Sodium hydroxide is used as a reagent:

• for the preparation of synthesis solution during the formation of LTA zeolite crystals in the hydrothermal synthesis process.
• in the synthesis of 2-line ferrihydrite (spHm) and rhombohedral Hm (rhHm) and as a base to adjust the pH of the mixed solution.
• to raise the pH of the HEPES buffer during catalytic reactivity to nanoparticle (CRNP) assay and synthesis.
• in the synthesis of zinc oxide nanoparticles from zinc chloride during lithium doping impact on the cathodoluminescence of the nanoparticles.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H290 - H314
• Precautionary Statements: P234 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1A
• Storage Class Code: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable