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Key Documents

MAB1578

Sigma-Aldrich

Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2

clone 18C7.2, Chemicon®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

18C7.2, monoclonal

purified by

using Protein A

species reactivity

monkey

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_000741.2

UniProt accession no.

P08173

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

rhesus monkey ... Chrm4(574195)

Specificity

m4 muscarinic acetylcholine receptor. No reactivity with the other subtypes.

Immunogen

m4 receptor i3 loop (human), fused to GST

Application

Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2 detects level of Muscarinic Acetylcholine Receptor m4 & has been published & validated for use in IH, IP & WB.
Immunohistochemistry (monkey)

Western blot (transfected CHO cell lines)

Immunoprecipitation (rat and monkey)

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Physical form

Liquid in 0.02M Phosphate buffer, 0.25 M NaCl with 0.1% sodium azide.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synaptic connections of starburst amacrine cells and localization of acetylcholine receptors in primate retinas.
Elizabeth S Yamada, Nina Dmitrieva, Kent T Keyser, Jon M Lindstrom, Louis B Hersh, David W Marshak
The Journal of Comparative Neurology null
Judith Molina et al.
Diabetes, 63(8), 2714-2726 (2014-03-25)
Acetylcholine regulates hormone secretion from the pancreatic islet and is thus crucial for glucose homeostasis. Little is known, however, about acetylcholine (cholinergic) signaling in the human islet. We recently reported that in the human islet, acetylcholine is primarily a paracrine

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