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934569

Sigma-Aldrich

NanoFabTx Photoactivatable Lipid

redAzoPC

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About This Item

Empirical Formula (Hill Notation):
C46H72Cl4N3O8P
CAS Number:
Molecular Weight:
967.86
UNSPSC Code:
12161503
NACRES:
NA.21

Quality Level

Assay

≥90%

form

solid

color

orange to dark red

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@H](OC(CCCC1=CC(Cl)=C(C(Cl)=C1)/N=N/C2=C(C=C(C=C2Cl)CCCC)Cl)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

General description

The NanoFabTx Photoactivatable Lipid, redAzoPC is a red-light photoswitchable lipid for controlled and targeted drug delivery. The tetra-ortho-chloro-azobenzene of redAzoPC can be isomerized from the cis to the trans conformation at 660 nm light. LNPs prepared using the NanoFabTx Photoactivatable Lipid, redAzoPC result in controlled drug release following deep red light irradiation.

Application

Lipid nanoparticle and liposome drug delivery systems

Features and Benefits

  • Similar drug loading, encapsulation efficiency, size, and polydispersity to non-photoswitchable lipids
  • Light-induced drug delivery
  • Targeted and controlled release
  • Overcomes limitations associated to UV-switchable lipids

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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