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Key Documents

89799

Sigma-Aldrich

1,3-Di-Boc-2-(2-hydroxyethyl)guanidine

≥96.0% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C13H25N3O5
CAS Number:
Molecular Weight:
303.35
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22

Assay

≥96.0% (HPLC)

form

powder

mp

120-125 °C

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)N\C(NC(=O)OC(C)(C)C)=N\CCO

InChI

1S/C13H25N3O5/c1-12(2,3)20-10(18)15-9(14-7-8-17)16-11(19)21-13(4,5)6/h17H,7-8H2,1-6H3,(H2,14,15,16,18,19)

InChI key

NHRGPOQWQFSEOH-UHFFFAOYSA-N

Other Notes

Guanidinylation reagent

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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K. Feichtinger et al.
The Journal of Organic Chemistry, 63, 8432-8432 (1998)
K C Nicolaou et al.
Bioorganic & medicinal chemistry, 6(8), 1185-1208 (1998-10-24)
Recent studies demonstrated that peptide and antibody antagonists of integrin alpha v beta 3 block angiogenesis and tumor growth. In this article, the design, synthesis and biological evaluation of a series of nitroaryl ether-based, nonpeptide mimetics are described. The design
Antoine Frère et al.
Biomacromolecules, 16(3), 769-779 (2015-01-21)
RNAi therapeutics are promising therapeutic tools that have sparked the interest of many researchers. In an effort to provide a safe alternative to PEI, we have designed a series of new guanidinium- and morpholino-functionalized biocompatible and biodegradable polycarbonate vectors. The

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