532363

(S)-(−)-1,2-Epoxybutane

98%

• Synonym(s): (2S)-Ethyloxirane
• Empirical Formula (Hill Notation): C₄H₈O
• CAS Number: 30608-62-9
• Molecular Weight: 72.11
• MDL number: MFCD02683445
• UNSPSC Code: 12352005
• PubChem Substance ID: 24877883
• NACRES: NA.22

Properties

• Assay: 98%
• optical activity: [α]20/D −10°, neat
• refractive index: n20/D 1.386 (lit.)
• bp: 63 °C (lit.)
• density: 0.837 g/mL at 25 °C (lit.)
• SMILES string: CC[C@H]1CO1
• InChI: 1S/C4H8O/c1-2-4-3-5-4/h4H,2-3H2,1H3/t4-/m0/s1
• InChI key: RBACIKXCRWGCBB-BYPYZUCNSA-N

Description

Application

(S)-(−)-1,2-Epoxybutane can be used:

• As a starting material to prepare (+)- and (−)-homononactic acids, which are used as intermediates in the total synthesis of a cyclic antibiotic tetranactin.
• To prepare a chiral phosphorus synthon, which is applicable in the synthesis of phytoprostane B1 type I.
• To prepare Eu³⁺-based precatalysts applicable in the Mukaiyama Aldol reaction in water.

Legal Information

Manufactured under license by Sterling Pharma Solutions Limited, using Jacobsen HKR technology.

Safety Information

• Pictograms: GHS02,GHS08,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H314,H351
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 10.0 °F - closed cup
• Flash Point(C): -12.2 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves